G57321FI

Summary
GlyTouCan ID
G57321FI
IUPAC Condensed
GalNAc(a1-
Motifs
Tn antigen
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
The Human Metabolome Database
3D Structures
GLYCAM
DGalpNAca1-OH
GlycoShape
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
Displaying entries 1 - 5 of 9 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G57321FI
benzyl
G36123IU
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[Ala-Thr(*)-Ala]2-7
G36123IU
[Ala-Thr(*)-Ala]2-7
Displaying entries 1 - 5 of 35 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST6GALNAC3 CMP-Neu5Ac
G57321FI
Ser/Thr
ST6GAL2 CMP-Neu5Ac
G57321FI
para-nitrophenol
ST6GALNAC2 CMP-Neu5Ac
G57321FI
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[alpha]-Bz
ST6GALNAC2 CMP-Neu5Ac
G57321FI
Ser/Thr
GlycoEpitope
Epitope ID
EP0021
Pathway
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n
WURCS
WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
Displaying entries 101 - 110 of 2052 in total
PubMed ID Title First Author Publication Date Source
35531651 Givosiran for the treatment of acute hepatic porphyria Ricci A 2022 Apr 03
  • PubChem
34826537 Structural and mechanistic insights into the substrate specificity and hydrolysis of GH31 α-N-acetylgalactosaminidase Miyazaki T 2022 Apr
  • PubChem
34510420 A Drug‐Drug Interaction Study Evaluating the Effect of Givosiran, a Small Interfering Ribonucleic Acid, on Cytochrome P450 Activity in the Liver Vassiliou D 2021 Sep 28
  • PubChem
34549685 Inhibition of O-glycosylation aggravates GalN/LPS-induced liver injury through activation of ER stress Xu D 2021 Sep 22
  • PubChem
34260280 Adeno-associated Virus 9 Structural Rearrangements Induced by Endosomal Trafficking pH and Glycan Attachment Penzes JJ 2021 Sep 09
  • PubChem
34126457 N-acetylgalactosamine-decorated nanoliposomes for targeted delivery of paclitaxel to hepatocellular carcinoma Li T 2021 Oct 15
  • PubChem
34648028 Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAs Schlegel MK 2021 Oct 14
  • PubChem
34616040 A single sulfatase is required to access colonic mucin by a gut bacterium Luis AS 2021 Oct 06
  • PubChem
34091052 Ligand conjugate SAR and enhanced delivery in NHP Holland RJ 2021 Oct 06
  • PubChem
34717041 Efficacy and safety of givosiran for acute hepatic porphyria: 24‐month interim analysis of the randomized phase 3 ENVISION study Ventura P 2021 Nov 16
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell-lymphatic endothelium interaction.
  • Danussi C
  • Coslovi A
  • Campa C
  • Mucignat MT
  • Spessotto P
  • Uggeri F
  • Paoletti S
  • Colombatti A
Glycobiology 2009 Oct 19528665
Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination.
  • Freire T
  • Lo-Man R
  • Piller F
  • Piller V
  • Leclerc C
  • Bay S
Glycobiology 2006 May 16449349
Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen.
  • Zhang Y
  • Iwasaki H
  • Wang H
  • Kudo T
  • Kalka TB
  • Hennet T
  • Kubota T
  • Cheng L
  • Inaba N
  • Gotoh M
  • Togayachi A
  • Guo J
  • Hisatomi H
  • Nakajima K
  • Nishihara S
  • Nakamura M
  • Marth JD
  • Narimatsu H
J Biol Chem 2003 Jan 3 12407114
Purification, characterization, and cDNA cloning of alpha-N-acetylgalactosamine-specific lectin from starfish, Asterina pectinifera.
  • Kakiuchi M
  • Okino N
  • Sueyoshi N
  • Ichinose S
  • Omori A
  • Kawabata S
  • Yamaguchi K
  • Ito M
Glycobiology 2002 Feb 11886841
Pursuit of optimal carbohydrate-based anticancer vaccines: preparation of a multiantigenic unimolecular glycopeptide containing the Tn, MBr1, and Lewis(y) antigens.
  • Allen JR
  • Harris CR
  • Danishefsky SJ
J Am Chem Soc 2001 Mar 7 11456809

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025