GlyCosmos Portal

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Organisms	Evidence
Ovis aries (sheep)	GlyTouCan(glycome-db)
Cricetulus griseus (Chinese hamster)	GlyTouCan(glycome-db)
Mus musculus (house mouse)	GlyConnectStructure GlyTouCan(glycome-db) GlycoEpitope
Bos taurus (domestic cattle)	GlyTouCan(glycome-db)
Escherichia coli	GlyTouCan(bcsdb)

Taxonomic Hierarchy

root

cellular organisms [inference]

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Escherichia [inference]

Escherichia coli

Pseudomonadales [inference]

Pseudomonadaceae [inference]

Pseudomonas [inference]

Pseudomonas aeruginosa group [inference]

Pseudomonas aeruginosa

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Cricetidae [inference]

Cricetinae (hamsters) [inference]

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Chlorocebus [inference]

Chlorocebus aethiops (grivet)

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Caprinae [inference]

Ovis [inference]

Ovis aries (sheep)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Crustacea (crustaceans) [inference]

Multicrustacea [inference]

Malacostraca [inference]

Eumalacostraca [inference]

Peracarida [inference]

Isopoda (pill bugs, wood lice and sea slaters) [inference]

Oniscidea (pillbugs) [inference]

Crinocheta [inference]

Armadillidae [inference]

Armadillo

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Calyptratae [inference]

Oestroidea [inference]

Calliphoridae (blowflies) [inference]

Chrysomyinae [inference]

Phormini [inference]

Protophormia [inference]

Protophormia terraenovae (northern blowfly)

Nematoda (roundworms) [inference]

Chromadorea [inference]

Rhabditida [inference]

Rhabditina [inference]

Rhabditomorpha [inference]

Strongyloidea (lungworms) [inference]

Heligmosomidae [inference]

Nippostrongylus [inference]

Nippostrongylus brasiliensis

Rhabditoidea [inference]

Rhabditidae [inference]

Peloderinae [inference]

Caenorhabditis [inference]

Caenorhabditis elegans

Spirurina [inference]

Ascaridomorpha [inference]

Ascaridoidea [inference]

Toxocaridae [inference]

Toxocara [inference]

Toxocara canis (dog roundworm)

Spiralia [inference]

Lophotrochozoa [inference]

Platyhelminthes (flatworms) [inference]

Cestoda (tapeworms) [inference]

Eucestoda [inference]

Cyclophyllidea [inference]

Taeniidae [inference]

Echinococcus [inference]

Echinococcus granulosus group [inference]

Echinococcus granulosus

Taenia [inference]

Taenia hydatigena

Mesocestoididae [inference]

Mesocestoides [inference]

Trematoda [inference]

Digenea (flukes) [inference]

Plagiorchiida [inference]

Echinostomata [inference]

Echinostomatoidea [inference]

Fasciolidae [inference]

Fasciola [inference]

Fasciola hepatica (liver fluke)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Viruses [inference]

Riboviria [inference]

Pararnavirae [inference]

Artverviricota [inference]

Revtraviricetes [inference]

Ortervirales [inference]

Retroviridae [inference]

Orthoretrovirinae [inference]

Lentivirus [inference]

Primate lentivirus group [inference]

unclassified Primate lentivirus group [inference]

Human immunodeficiency virus

Human immunodeficiency virus 1

Orthornavirae [inference]

Pisuviricota [inference]

Pisoniviricetes [inference]

Nidovirales [inference]

Cornidovirineae [inference]

Coronaviridae [inference]

Orthocoronavirinae [inference]

Betacoronavirus [inference]

Sarbecovirus [inference]

Severe acute respiratory syndrome-related coronavirus [inference]

Severe acute respiratory syndrome coronavirus 2

GlycoGene Database (GGDB)

Displaying **all 4** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
B3GNT6	UDP-GlcNAc	G57321FI	[alpha]-pNP	G00035MO	[alpha]-pNP	11821425

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC4	CMP-Neu5Ac	G57321FI	benzyl	G36123IU	benzyl	11062056
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
ST6GALNAC1	CMP-Neu5Ac	G57321FI	[Ala-Thr(*)-Ala]2-7	G36123IU	[Ala-Thr(*)-Ala]2-7	10536037

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GALNAC3	CMP-Neu5Ac	G57321FI	Ser/Thr	10536037
ST6GAL2	CMP-Neu5Ac	G57321FI	para-nitrophenol	12603328
ST6GALNAC2	CMP-Neu5Ac	G57321FI	benzyl	10742600 11062056
ST6GALNAC1	CMP-Neu5Ac	G57321FI	[alpha]-Bz	10536037
ST6GALNAC2	CMP-Neu5Ac	G57321FI	Ser/Thr	10536037

KEGG BRITE Database

KEGG ID

G00023

Enzyme

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05908	2.4.1.122	G57321FI	G00031MO
R05910	2.4.1.102 2.4.1.148	G57321FI	G00041MO
R05911	2.4.3.3	G57321FI	G36123IU
R05909	2.4.1.147	G57321FI	G00035MO

Core Protein

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UniProt ID	Protein Name	Reference	Source
Q9UH99	SUN domain-containing protein 2	23584533	GlyGen
Q9UHF1	Epidermal growth factor-like protein 7	23584533	GlyGen
Q9UHG2	ProSAAS	23584533	GlyGen
Q9UHI8	A disintegrin and metalloproteinase with thrombospondin motifs 1	23584533	GlyGen
Q9UIQ6	Leucyl-cystinyl aminopeptidase	23584533	GlyGen
Q9UIW2	Plexin-A1	23584533 25813380	GlyGen
Q9UJA9	Ectonucleotide pyrophosphatase/phosphodiesterase family member 5	23584533	GlyGen
Q9UJH8	Meteorin	23584533	GlyGen
Q9UJJ9	N-acetylglucosamine-1-phosphotransferase subunit gamma	23584533 25813380	GlyGen
Q9UKM7	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	23584533 25813380	GlyGen

GlycoEpitope

Epitope ID: EP0021

Pathway

Displaying entries **51 - 57** of 57 in total

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Pathway Name	Organism
Lectin pathway of complement activation	Bos taurus
Lectin pathway of complement activation	Rattus norvegicus
Lectin pathway of complement activation	Mus musculus
Lectin pathway of complement activation	Homo sapiens
Lectin pathway of complement activation	Xenopus tropicalis
Lectin pathway of complement activation	Gallus gallus
Lectin pathway of complement activation	Canis familiaris

Sequence Descriptors

GlycoCT

RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n

WURCS

WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/

Literature

Displaying entries **891 - 900** of **2052** in total

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PubMed ID	Title	First Author	Publication Date	Source
12049210	Structure and function of the Entamoeba histolytica Gal/GalNAc lectin	Mann BJ	2002	PubChem
11550228	Developmental expression of a unique carbohydrate antigen, Tn antigen, in mouse central nervous tissues	Akita K	2001 Sep 15	GlyGen GlycoEpitope
11549261	Distinct Orders of GalNAc Incorporation into a Peptide with Consecutive Threonines	Kato K	2001 Sep 14	PubChem
11525994	UDP- N -Acetylglucosamine 4-Epimerase Activity Indicates the Presence of N -Acetylgalactosamine in Exopolysaccharides of Streptococcus thermophilus Strains	Degeest B	2001 Sep	PubChem
11748625	Surface glycoproteins bearing alpha-GalNAc terminated chains accompany pyriform cell differentiation in lizards	Uliano R	2001 Oct 30	PubChem
11514575	Molecular Cloning and Expression of a Human Chondroitin Synthase	Kitagawa H	2001 Oct 19	PubChem
11592774	GalNAc glycoprotein expression by breast cell lines, primary breast cancer and normal breast epithelial membrane	Brooks SA	2001 Oct 02	PubChem
11588158	N-acetylgalactosamine incorporation into a peptide containing consecutive threonine residues by UDP-N-acetyl-D-galactosaminide:polypeptide N-acetylgalactosaminyltransferases	Kato K	2001 Oct 01	PubChem
11578961	Inhibition of the glycosylation and alteration in the intracellular trafficking of mucins and other glycoproteins by GalNAcalpha-O-bn in mucosal cell lines: an effect mediated through the intracellular synthesis of complex GalNAcalpha-O-bn oligosaccharides	Gouyer V	2001 Oct 01	PubChem
12441670	Boundary lubrication by lubricin is mediated by O-linked beta(1-3)Gal-GalNAc oligosaccharides	Jay GD	2001 Oct	PubChem

PubAnnotation

Displaying entries **1 - 5** of 9 in total

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Title	Authors	Source	Publication Date	PubMed ID
A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell-lymphatic endothelium interaction.	Danussi C Coslovi A Campa C Mucignat MT Spessotto P Uggeri F Paoletti S Colombatti A	Glycobiology	2009 Oct	19528665
Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination.	Freire T Lo-Man R Piller F Piller V Leclerc C Bay S	Glycobiology	2006 May	16449349
Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen.	Zhang Y Iwasaki H Wang H Kudo T Kalka TB Hennet T Kubota T Cheng L Inaba N Gotoh M Togayachi A Guo J Hisatomi H Nakajima K Nishihara S Nakamura M Marth JD Narimatsu H	J Biol Chem	2003 Jan 3	12407114
Purification, characterization, and cDNA cloning of alpha-N-acetylgalactosamine-specific lectin from starfish, Asterina pectinifera.	Kakiuchi M Okino N Sueyoshi N Ichinose S Omori A Kawabata S Yamaguchi K Ito M	Glycobiology	2002 Feb	11886841
Pursuit of optimal carbohydrate-based anticancer vaccines: preparation of a multiantigenic unimolecular glycopeptide containing the Tn, MBr1, and Lewis(y) antigens.	Allen JR Harris CR Danishefsky SJ	J Am Chem Soc	2001 Mar 7	11456809

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements