G57321FI
| Organisms | Evidence | 
|---|---|
| Pseudomonas aeruginosa | |
| Macaca mulatta (Rhesus monkey) | |
| Toxocara canis (dog roundworm) | |
| Drosophila melanogaster (fruit fly) | |
| Caenorhabditis elegans | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference | 
|---|---|---|---|---|---|---|
| C1GALT1 | (not applicable) | 
                          
                             | 
                    Ser/Thr | 
                          
                             | 
                    Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    Ser/Thr | 
                          
                             | 
                    Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    O-glycan Synthesis | 
                          
                             | 
                    O-glycan Synthesis | |
| B3GNT6 | UDP-GlcNAc | 
                          
                             | 
                    [alpha]-pNP | 
                          
                             | 
                    [alpha]-pNP | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference | 
|---|---|---|---|---|---|---|
| C1GALT1 | (not applicable) | 
                          
                             | 
                    Ser/Thr | 
                          
                             | 
                    Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    Ser/Thr | 
                          
                             | 
                    Ser/Thr | |
| ST6GALNAC4 | CMP-Neu5Ac | 
                          
                             | 
                    benzyl | 
                          
                             | 
                    benzyl | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    O-glycan Synthesis | 
                          
                             | 
                    O-glycan Synthesis | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    [Ala-Thr(*)-Ala]2-7 | 
                          
                             | 
                    [Ala-Thr(*)-Ala]2-7 | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Reference | 
|---|---|---|---|---|
| ST6GALNAC3 | CMP-Neu5Ac | 
                          
                             | 
                    Ser/Thr | |
| ST6GAL2 | CMP-Neu5Ac | 
                          
                             | 
                    para-nitrophenol | |
| ST6GALNAC2 | CMP-Neu5Ac | 
                          
                             | 
                    benzyl | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    [alpha]-Bz | |
| ST6GALNAC2 | CMP-Neu5Ac | 
                          
                             | 
                    Ser/Thr | 
| UniProt ID | Protein Name | Reference | Source | 
|---|---|---|---|
| Q9UKP4 | A disintegrin and metalloproteinase with thrombospondin motifs 7 | ||
| Q9UKU9 | Angiopoietin-related protein 2 | ||
| Q9ULB5 | Cadherin-7 | ||
| Q9ULC8 | Palmitoyltransferase ZDHHC8 | ||
| Q9ULF5 | Zinc transporter ZIP10 | ||
| Q9ULI3 | Protein HEG homolog 1 | ||
| Q9UMD9 | Collagen alpha-1(XVII) chain | ||
| Q9UMX5 | Neudesin | ||
| Q9UNA0 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | ||
| Q9UNE0 | Tumor necrosis factor receptor superfamily member EDAR | 
| Pathway Name | Organism | 
|---|---|
| Lectin pathway of complement activation | Bos taurus | 
| Lectin pathway of complement activation | Rattus norvegicus | 
| Lectin pathway of complement activation | Mus musculus | 
| Lectin pathway of complement activation | Homo sapiens | 
| Lectin pathway of complement activation | Xenopus tropicalis | 
| Lectin pathway of complement activation | Gallus gallus | 
| Lectin pathway of complement activation | Canis familiaris | 
RES 1b:a-dgal-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
| PubMed ID | Title | First Author | Publication Date | Source | 
|---|---|---|---|---|
| 38839445 | Personalized dosage of Givosiran in acute intermittent porphyria | Garrido Montes M | 2024 Sep 13 | 
                  
  | 
          
| 39232672 | Role of the GalNAc-galectin pathway in the healing of premature rupture of membranes | Chen JL | 2024 Sep 04 | 
                  
  | 
          
| 39222205 | RNAi targeting LMAN1-MCFD2 complex promotes anticoagulation in mice | Ma S | 2024 Sep 02 | 
                  
  | 
          
| 39477529 | Development of bioconjugate-based delivery systems for nucleic acids | Wahane A | 2024 Oct 30 | 
                  
  | 
          
| 39168524 | Nonclinical Pharmacokinetics Study of OLX702A-075-16, N-Acetylgalactosamine Conjugated Asymmetric Small Interfering RNA (GalNAc-asiRNA) | Ban J | 2024 Oct 16 | 
                  
  | 
          
| 39379811 | The utilization of N-acetylgalactosamine and its effect on the metabolism of amino acids in Erysipelotrichaceae strain | Zhou M | 2024 Oct 09 | 
                  
  | 
          
| 39361617 | Aglycone Analysis and Quantitative Tracking of Correlated Terminal Glycan Pair on Spermatozoa | Xu L | 2024 Oct 03 | 
                  
  | 
          
| 39363243 | Long-term follow-up of givosiran treatment in patients with acute intermittent porphyria from a phase 1/2, 48-month open-label extension study | Sardh E | 2024 Oct 03 | 
                  
  | 
          
| 38992557 | Canadian guidance for diagnosis and management of acute hepatic porphyrias | Francisco Idiaquez J | 2024 Oct | 
                  
  | 
          
| 39528231 | Improved In Vivo Metabolic Stability and Silencing Efficacy of siRNAs with Phosphorothioate Linkage-Free, GalNAc-Conjugated Sense Strands Containing Morpholino-LNA Modifications | Datta D | 2024 Nov 11 | 
                  
  | 
          
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: August 4, 2025