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GlyTouCan
Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
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G57321FI
Summary
- GlyTouCan ID
-
G57321FI
- IUPAC Condensed
- GalNAc(a1-
- Motifs
- Tn antigen
Organisms
| Organisms | Evidence |
|---|---|
| Ovis aries (sheep) | |
| Cricetulus griseus (Chinese hamster) | |
| Mus musculus (house mouse) | |
| Bos taurus (domestic cattle) | |
| Escherichia coli |
Taxonomic Hierarchy
root
cellular organisms [inference]
Eukaryota (eucaryotes) [inference]
Opisthokonta [inference]
Metazoa (metazoans) [inference]
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| C1GALT1 | (not applicable) |
G57321FI
|
Ser/Thr |
G00031MO
|
Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
Ser/Thr |
G36123IU
|
Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
O-glycan Synthesis |
G36123IU
|
O-glycan Synthesis | |
| B3GNT6 | UDP-GlcNAc |
G57321FI
|
[alpha]-pNP |
G00035MO
|
[alpha]-pNP |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| C1GALT1 | (not applicable) |
G57321FI
|
Ser/Thr |
G00031MO
|
Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
Ser/Thr |
G36123IU
|
Ser/Thr | |
| ST6GALNAC4 | CMP-Neu5Ac |
G57321FI
|
benzyl |
G36123IU
|
benzyl | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
O-glycan Synthesis |
G36123IU
|
O-glycan Synthesis | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
[Ala-Thr(*)-Ala]2-7 |
G36123IU
|
[Ala-Thr(*)-Ala]2-7 |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Reference |
|---|---|---|---|---|
| ST6GALNAC3 | CMP-Neu5Ac |
G57321FI
|
Ser/Thr | |
| ST6GAL2 | CMP-Neu5Ac |
G57321FI
|
para-nitrophenol | |
| ST6GALNAC2 | CMP-Neu5Ac |
G57321FI
|
benzyl | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
[alpha]-Bz | |
| ST6GALNAC2 | CMP-Neu5Ac |
G57321FI
|
Ser/Thr |
KEGG BRITE Database
G00041MO
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| Q9C002 | Normal mucosa of esophagus-specific gene 1 protein | ||
| Q9C0B5 | Palmitoyltransferase ZDHHC5 | ||
| Q9C0D2 | Centrosomal protein of 295 kDa | ||
| Q9GZM5 | Protein YIPF3 | ||
| Q9GZP4 | PITH domain-containing protein 1 | ||
| Q9GZZ8 | Extracellular glycoprotein lacritin | ||
| Q9H013 | Disintegrin and metalloproteinase domain-containing protein 19 | ||
| Q9H173 | Nucleotide exchange factor SIL1 | ||
| Q9H1B5 | Xylosyltransferase 2 | ||
| Q9H1U4 | Multiple epidermal growth factor-like domains protein 9 |
GlycoEpitope
- Epitope ID
- EP0021
Pathway
| Pathway Name | Organism |
|---|---|
| E.coli O101 | Escherichia coli |
| E.coli O103 | Escherichia coli |
| E.coli O107 | Escherichia coli |
| E.coli O112ab | Escherichia coli |
| E.coli O112ac | Escherichia coli |
| E.coli O116 | Escherichia coli |
| E.coli O117 | Escherichia coli |
| E.coli O125ab | Escherichia coli |
| E.coli O127 | Escherichia coli |
| E.coli O128ab-H27 | Escherichia coli |
Sequence Descriptors
- GlycoCT
-
RES 1b:a-dgal-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 38522000 | Model‐based meta‐analysis to quantify the effects of short interfering <scp>RNA</scp> therapeutics on hepatitis B surface antigen turnover in hepatitis B‐infected mice | Sandra L | 2024 Mar 24 |
|
| 38204163 | Application of improved GalNAc conjugation in development of cost-effective siRNA therapies targeting cardiovascular diseases | Li Q | 2024 Mar 06 |
|
| 38416819 | An unusual dual sugar-binding lectin domain controls the substrate specificity of a mucin-type O-glycosyltransferase | Collette AM | 2024 Mar |
|
| 38860868 | Incorporation of Intracellular NanoSIMS Tracers to Oligonucleotide Conjugates via Strain Promoted Sydnone–Alkyne Cycloaddition | Lincy-Bianchi L | 2024 Jun 11 |
|
| 38044204 | A randomized, placebo-controlled study of givosiran in patients with acute hepatic porphyrias (ENVISION): Final (36-month) analysis of the Taiwan Cohort | Lee M | 2024 Jun |
|
| 38993155 | A GalNAc-modified CaCO3 nano-immunomodulator for targeted and responsive immunotherapy against orthotopic liver cancer | Li Y | 2024 Jul 30 |
|
| 38795858 | Bifunctional glycosphingolipid (GSL) probes to investigate GSL-interacting proteins in cell membranes | Kundu S | 2024 Jul |
|
| 38172637 | Host genetic regulation of human gut microbial structural variation | Zhernakova DV | 2024 Jan 03 |
|
| 38409587 | RNA interference in the era of nucleic acid therapeutics | Jadhav V | 2024 Feb 26 |
|
| 38535445 | Cloning and Characterization of a Novel N-Acetyl-D-galactosamine-4-O-sulfate Sulfatase, SulA1, from a Marine Arthrobacter Strain | Christensen MD | 2024 Feb 23 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| Immunological response from an entirely carbohydrate antigen: design of synthetic vaccines based on Tn-PS A1 conjugates. |
|
J Am Chem Soc | 2009 Jul 22 | 19552408 |
| Two different glycosyltransferase defects that result in GalNAc alpha-O-peptide (Tn) expression. |
|
Glycobiology | 1994 Jun | 7949653 |
| Localization of O-glycan initiation, sphingomyelin synthesis, and glucosylceramide synthesis in Vero cells with respect to the endoplasmic reticulum-Golgi intermediate compartment. |
|
J Biol Chem | 1994 Feb 11 | 8307959 |
| Carbohydrate receptor-mediated gene transfer to human T leukaemic cells. |
|
Glycobiology | 1994 Aug | 7827404 |
