G57321FI

Summary
GlyTouCan ID
G57321FI
IUPAC Condensed
GalNAc(a1-
Motifs
Tn antigen
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
The Human Metabolome Database
3D Structures
GlycoNAVI
G57321FI
GLYCAM
DGalpNAca1-OH
GlycoShape
Organisms
Displaying entry 26 - 26 of 26 in total
Organisms Evidence
Human immunodeficiency virus 1
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
Displaying entries 1 - 5 of 9 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G57321FI
benzyl
G36123IU
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[Ala-Thr(*)-Ala]2-7
G36123IU
[Ala-Thr(*)-Ala]2-7
Displaying entries 1 - 5 of 35 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST6GALNAC3 CMP-Neu5Ac
G57321FI
Ser/Thr
ST6GAL2 CMP-Neu5Ac
G57321FI
para-nitrophenol
ST6GALNAC2 CMP-Neu5Ac
G57321FI
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[alpha]-Bz
ST6GALNAC2 CMP-Neu5Ac
G57321FI
Ser/Thr
GlycoEpitope
Epitope ID
EP0021
Pathway
Displaying entries 1 - 10 of 57 in total
Pathway Name Organism
E.coli O101 Escherichia coli
E.coli O103 Escherichia coli
E.coli O107 Escherichia coli
E.coli O112ab Escherichia coli
E.coli O112ac Escherichia coli
E.coli O116 Escherichia coli
E.coli O117 Escherichia coli
E.coli O125ab Escherichia coli
E.coli O127 Escherichia coli
E.coli O128ab-H27 Escherichia coli
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n
WURCS
WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
Displaying entries 711 - 720 of 2052 in total
PubMed ID Title First Author Publication Date Source
16525726 The influence of N- and O-glycosylation inhibitors on the glycosylation profile of cellular membrane proteins and adhesive properties of carcinoma cell lines Paszkiewicz-Gadek A 2006 Apr
  • GlyGen
  • GlycoEpitope
16624894 N-Acetylgalactosamine 4,6-O-sulfate residues mediate binding and activation of heparin cofactor II by porcine mucosal dermatan sulfate Halldórsdóttir AM 2006 Apr 19
  • PubChem
16615117 Interference with O-glycosylation in RMA lymphoma cells leads to a reduced in vivo growth of the tumor Chen L 2006 Apr 13
  • GlyGen
  • GlycoEpitope
  • PubChem
16609676 Pathogenic IgA in IgA nephropathy: still the blind men and the elephant? Lai KN 2006 Apr
  • PubChem
15864746 Polyvalent GalNAcalpha1-->Ser/Thr (Tn) and Galbeta1-->3GalNAcalpha1-->Ser/Thr (T alpha) as the most potent recognition factors involved in Maclura pomifera agglutinin-glycan interactions Wu AM 2005
  • GlyGen
  • GlycoEpitope
15864747 Further characterization of the binding properties of two monoclonal antibodies recognizing human Tn red blood cells Wua AM 2005
  • GlyGen
  • GlycoEpitope
15864748 Lectinochemical studies on the glyco-recognition factors of a Tn (GalNAcalpha1-->Ser/Thr) specific lectin isolated from the seeds of Salvia sclarea Wu AM 2005
  • GlyGen
  • GlycoEpitope
16006554 The Molecular Architecture of Human N-Acetylgalactosamine Kinase Thoden JB 2005 Sep 23
  • PubChem
16174741 Distinct functional units of the Golgi complex in Drosophila cells Yano H 2005 Sep 20
  • GlyGen
  • GlycoEpitope
16297170 The glycans deficiencies of macromolecular IgA1 is a contributory factor of variable pathological phenotypes of IgA nephropathy Xu LX 2005 Sep 11
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 9 in total
Title Authors Source Publication Date PubMed ID
The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.
  • Coelho H
  • Matsushita T
  • Artigas G
  • Hinou H
  • Cañada FJ
  • Lo-Man R
  • Leclerc C
  • Cabrita EJ
  • Jiménez-Barbero J
  • Nishimura S
  • Garcia-Martín F
  • Marcelo F
J Am Chem Soc 2015 Oct 7 26366611
Single molecule study of heterotypic interactions between mucins possessing the Tn cancer antigen.
  • Haugstad KE
  • Stokke BT
  • Brewer CF
  • Gerken TA
  • Sletmoen M
Glycobiology 2015 May 25527429
Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice.
  • Song K
  • Herzog BH
  • Fu J
  • Sheng M
  • Bergstrom K
  • McDaniel JM
  • Kondo Y
  • McGee S
  • Cai X
  • Li P
  • Chen H
  • Xia L
J Biol Chem 2015 Aug 14 26124270
Identification of distinct glycoforms of IgA1 in plasma from patients with immunoglobulin A (IgA) nephropathy and healthy individuals.
  • Lehoux S
  • Mi R
  • Aryal RP
  • Wang Y
  • Schjoldager KT
  • Clausen H
  • van Die I
  • Han Y
  • Chapman AB
  • Cummings RD
  • Ju T
Mol Cell Proteomics 2014 Nov 25071157
Human T cell activation results in extracellular signal-regulated kinase (ERK)-calcineurin-dependent exposure of Tn antigen on the cell surface and binding of the macrophage galactose-type lectin (MGL).
  • van Vliet SJ
  • Vuist IM
  • Lenos K
  • Tefsen B
  • Kalay H
  • García-Vallejo JJ
  • van Kooyk Y
J Biol Chem 2013 Sep 20 23918927

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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