G57321FI

Summary
GlyTouCan ID
G57321FI
IUPAC Condensed
GalNAc(a1-
Motifs
Tn antigen
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
The Human Metabolome Database
3D Structures
GlycoNAVI
G57321FI
GLYCAM
DGalpNAca1-OH
GlycoShape
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
Displaying entries 1 - 5 of 9 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G57321FI
benzyl
G36123IU
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[Ala-Thr(*)-Ala]2-7
G36123IU
[Ala-Thr(*)-Ala]2-7
Displaying entries 1 - 5 of 35 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST6GALNAC3 CMP-Neu5Ac
G57321FI
Ser/Thr
ST6GAL2 CMP-Neu5Ac
G57321FI
para-nitrophenol
ST6GALNAC2 CMP-Neu5Ac
G57321FI
benzyl
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[alpha]-Bz
ST6GALNAC2 CMP-Neu5Ac
G57321FI
Ser/Thr
GlycoEpitope
Epitope ID
EP0021
Pathway
Displaying entries 1 - 10 of 57 in total
Pathway Name Organism
E.coli O101 Escherichia coli
E.coli O103 Escherichia coli
E.coli O107 Escherichia coli
E.coli O112ab Escherichia coli
E.coli O112ac Escherichia coli
E.coli O116 Escherichia coli
E.coli O117 Escherichia coli
E.coli O125ab Escherichia coli
E.coli O127 Escherichia coli
E.coli O128ab-H27 Escherichia coli
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n
WURCS
WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
Displaying entries 81 - 90 of 2052 in total
PubMed ID Title First Author Publication Date Source
35058124 Givosiran in acute intermittent porphyria: A personalized medicine approach Poli A 2022 Mar
  • PubChem
35737426 Preclinical Toxicological Assessment of A Novel siRNA, SLN360, Targeting Elevated Lipoprotein (a) in Cardiovascular Disease Rider D 2022 Jun 23
  • PubChem
35745067 Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes Clua A 2022 Jun 20
  • PubChem
35734365 Spotlight on Givosiran as a Treatment Option for Adults with Acute Hepatic Porphyria: Design, Development, and Place in Therapy Majeed CN 2022 Jun
  • PubChem
34154993 The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human McDougall R 2022 Jun
  • PubChem
35887043 Identification of Multiple Domains of Entamoeba histolytica Intermediate Subunit Lectin-1 with Hemolytic and Cytotoxic Activities Kato K 2022 Jul 12
  • PubChem
35791075 Glucose Transport through N-Acetylgalactosamine Phosphotransferase System in Escherichia coli C Strain Kim HJ 2022 Jul 04
  • PubChem
35067977 RNAi therapy with givosiran significantly reduces attack rates in acute intermittent porphyria Sardh E 2022 Jan 23
  • PubChem
35053234 Towards Mapping of the Human Brain N-Glycome with Standardized Graphitic Carbon Chromatography Helm J 2022 Jan 06
  • PubChem
34871941 Purification of N-acetylgalactosamine-modified-oligonucleotides using orthogonal anion-exchange and mixed-mode chromatography approaches Kazarian AA 2022 Jan 04
  • PubChem
PubAnnotation
Displaying entries 6 - 9 of 9 in total
Title Authors Source Publication Date PubMed ID
Immunological response from an entirely carbohydrate antigen: design of synthetic vaccines based on Tn-PS A1 conjugates.
  • De Silva RA
  • Wang Q
  • Chidley T
  • Appulage DK
  • Andreana PR
J Am Chem Soc 2009 Jul 22 19552408
Two different glycosyltransferase defects that result in GalNAc alpha-O-peptide (Tn) expression.
  • King MJ
  • Chan A
  • Roe R
  • Warren BF
  • Dell A
  • Morris HR
  • Bartolo DC
  • Durdey P
  • Corfield AP
Glycobiology 1994 Jun 7949653
Localization of O-glycan initiation, sphingomyelin synthesis, and glucosylceramide synthesis in Vero cells with respect to the endoplasmic reticulum-Golgi intermediate compartment.
  • Schweizer A
  • Clausen H
  • van Meer G
  • Hauri HP
J Biol Chem 1994 Feb 11 8307959
Carbohydrate receptor-mediated gene transfer to human T leukaemic cells.
  • Thurnher M
  • Wagner E
  • Clausen H
  • Mechtler K
  • Rusconi S
  • Dinter A
  • Birnstiel ML
  • Berger EG
  • Cotten M
Glycobiology 1994 Aug 7827404

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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