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G57321FI

Summary

GlyTouCan ID: G57321FI
IUPAC Condensed: GalNAc(a1-
Motifs: Tn antigen

External Links

GlyGen

G57321FI

3D Structures

GLYCAM: DGalpNAca1-OH

GlycoShape

G57321FI

Organisms

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Organisms	Evidence
Fasciola hepatica (liver fluke)	GlycoEpitope
Toxocara canis (dog roundworm)	GlycoEpitope
Echinococcus granulosus	GlycoEpitope
Oryctolagus cuniculus (rabbit)	GlyTouCan(glycome-db)
Ovis aries (sheep)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Protostomia [inference]

Ecdysozoa [inference]

Nematoda (roundworms) [inference]

Chromadorea [inference]

Rhabditida [inference]

Spirurina [inference]

Ascaridomorpha [inference]

Ascaridoidea [inference]

Toxocaridae [inference]

Toxocara [inference]

Toxocara canis (dog roundworm)

Rhabditina [inference]

Rhabditomorpha [inference]

Strongyloidea (lungworms) [inference]

Heligmosomidae [inference]

Nippostrongylus [inference]

Nippostrongylus brasiliensis

Rhabditoidea [inference]

Rhabditidae [inference]

Peloderinae [inference]

Caenorhabditis [inference]

Caenorhabditis elegans

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Calyptratae [inference]

Oestroidea [inference]

Calliphoridae (blowflies) [inference]

Chrysomyinae [inference]

Phormini [inference]

Protophormia [inference]

Protophormia terraenovae (northern blowfly)

Crustacea (crustaceans) [inference]

Multicrustacea [inference]

Malacostraca [inference]

Eumalacostraca [inference]

Peracarida [inference]

Isopoda (pill bugs, wood lice and sea slaters) [inference]

Oniscidea (pillbugs) [inference]

Crinocheta [inference]

Armadillidae [inference]

Armadillo

Spiralia [inference]

Lophotrochozoa [inference]

Platyhelminthes (flatworms) [inference]

Cestoda (tapeworms) [inference]

Eucestoda [inference]

Cyclophyllidea [inference]

Mesocestoididae [inference]

Mesocestoides [inference]

Taeniidae [inference]

Taenia [inference]

Taenia hydatigena

Echinococcus [inference]

Echinococcus granulosus group [inference]

Echinococcus granulosus

Trematoda [inference]

Digenea (flukes) [inference]

Plagiorchiida [inference]

Echinostomata [inference]

Echinostomatoidea [inference]

Fasciolidae [inference]

Fasciola [inference]

Fasciola hepatica (liver fluke)

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Cricetidae [inference]

Cricetinae (hamsters) [inference]

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Chlorocebus [inference]

Chlorocebus aethiops (grivet)

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Ovis aries (sheep)

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Escherichia [inference]

Escherichia coli

Pseudomonadales [inference]

Pseudomonadaceae [inference]

Pseudomonas [inference]

Pseudomonas aeruginosa group [inference]

Pseudomonas aeruginosa

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Pisuviricota [inference]

Pisoniviricetes [inference]

Nidovirales [inference]

Cornidovirineae [inference]

Coronaviridae [inference]

Orthocoronavirinae [inference]

Betacoronavirus [inference]

Sarbecovirus [inference]

Severe acute respiratory syndrome-related coronavirus [inference]

Severe acute respiratory syndrome coronavirus 2

Pararnavirae [inference]

Artverviricota [inference]

Revtraviricetes [inference]

Ortervirales [inference]

Retroviridae [inference]

Orthoretrovirinae [inference]

Lentivirus [inference]

Human immunodeficiency virus 1

Primate lentivirus group [inference]

unclassified Primate lentivirus group [inference]

Human immunodeficiency virus

GlycoGene Database (GGDB)

Displaying **all 4** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
B3GNT6	UDP-GlcNAc	G57321FI	[alpha]-pNP	G00035MO	[alpha]-pNP	11821425

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC4	CMP-Neu5Ac	G57321FI	benzyl	G36123IU	benzyl	11062056
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
ST6GALNAC1	CMP-Neu5Ac	G57321FI	[Ala-Thr(*)-Ala]2-7	G36123IU	[Ala-Thr(*)-Ala]2-7	10536037

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GALNAC2	CMP-Neu5Ac	G57321FI	para-nitrophenol	10742600
ST6GALNAC1	CMP-Neu5Ac	G57321FI	[alpha]-Bz	10536037
ST6GALNAC3	CMP-Neu5Ac	G57321FI	Ser/Thr	10536037
ST6GALNAC2	CMP-Neu5Ac	G57321FI	Ser/Thr	10536037
ST6GAL2	CMP-Neu5Ac	G57321FI	para-nitrophenol	12603328

Core Protein

Displaying entries **1 - 10** of **819** in total

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UniProt ID	Protein Name	Reference	Source
A1A5C7	Solute carrier family 22 member 23	23584533	GlyGen
A1L4H1	Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D	23584533	GlyGen
A6NH11	Glycolipid transfer protein domain-containing protein 2	23584533	GlyGen
A6NLU5	V-set and transmembrane domain-containing protein 2B	23584533	GlyGen
C9J069	Apical junction component 1 homolog	23584533 25813380	GlyGen
C9JH25	Proline-rich transmembrane protein 4	23584533	GlyGen
D9N008	Epiglycanin	1125949 115878	GlyConnect
O00151	PDZ and LIM domain protein 1	23584533	GlyGen
O00220	Tumor necrosis factor receptor superfamily member 10A	23584533 25813380	GlyGen
O00238	Bone morphogenetic protein receptor type-1B	23584533	GlyGen

Pathway

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Pathway Name	Organism
E.coli O101	Escherichia coli
E.coli O103	Escherichia coli
E.coli O107	Escherichia coli
E.coli O112ab	Escherichia coli
E.coli O112ac	Escherichia coli
E.coli O116	Escherichia coli
E.coli O117	Escherichia coli
E.coli O125ab	Escherichia coli
E.coli O127	Escherichia coli
E.coli O128ab-H27	Escherichia coli

Literature

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PubMed ID	Title	First Author	Publication Date	Source
8631864	Characterization of an alternatively spliced GM2 activator protein, GM2A protein. An activator protein which stimulates the enzymatic hydrolysis of N-acetylneuraminic acid, but not N-acetylgalactosamine, from GM2	Wu YY	1996 May 03	PubChem
8616877	Expression of Tn and sialyl-Tn antigens in the neoplastic transformation of uterine cervical epithelial cells	Terasawa K	1996 May 01	GlyGen GlycoEpitope
8804973	A polyreactive human anti-lipid A monoclonal antibody having cross reactivity to polysaccharide portions ofPseudomonas aeruginosalipopolysaccharides	Yokota S	1996 May	PubChem
8623771	Expression of mucin carbohydrate antigens (T, Tn and sialyl Tn) and MUC-1 gene product in intraductal papillary-mucinous neoplasm of the pancreas	Terada T	1996 May	GlyGen GlycoEpitope
8641988	Effect of MUC1 Mucin, an Anti‐adhesion Molecule, on Tumor Cell Growth	Makiguchi Y	1996 May	PubChem
8699416	Lectin histochemistry in the human epididymis	Arenas MI	1996 Mar 01	PubChem
8728711	Two N-acetyl-d-galactosamine-specific lectins from Phaeolepiota aurea	Kawagishi H	1996 Mar	PubChem
8793806	Association of asialo-galactosyl beta 1-3N-acetylgalactosamine on the hinge with a conformational instability of Jacalin-reactive immunoglobulin A1 in immunoglobulin A nephropathy.	Hiki Y	1996 Jun	PubChem
8744012	NMR studies on human, pathologically changed synovial fluids: Role of hypochlorous acid	Schiller J	1996 Jun	PubChem
8864849	Abundance of Gal beta 1,3GalNAc in O-linked oligosaccharide on hinge region of polymerized IgA1 and heat-aggregated IgA1 from normal human serum	Iwase H	1996 Jul 01	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
Tn-syndrome.	Berger EG	Biochim Biophys Acta	1999 Oct 8	10571017
Application of chemically desialylated and degalactosylated human glycophorin for induction and characterization of anti-Tn monoclonal antibodies.	Duk M Steuden I Duś D Radzikowski C Lisowska E	Glycoconj J	1992 Jun	1422133
Specificity of Amaranthus leucocarpus lectin.	Zenteno E Lascurain R Montaño LF Vazquez L Debray H Montreuil J	Glycoconj J	1992 Aug	1422141
Blood group Tn-active macromolecules from human carcinomas and erythrocytes: characterization of and specific reactivity with mono- and poly-clonal anti-Tn antibodies induced by various immunogens.	Springer GF Chandrasekaran EV Desai PR Tegtmeyer H	Carbohydr Res	1988 Jul 15	3056614

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