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G57321FI

Summary

GlyTouCan ID: G57321FI
IUPAC Condensed: GalNAc(a1-
Motifs: Tn antigen

External Links

GlyGen

G57321FI

3D Structures

GLYCAM: DGalpNAca1-OH

GlycoShape

G57321FI

Organisms

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Organisms	Evidence
Fasciola hepatica (liver fluke)	GlycoEpitope
Toxocara canis (dog roundworm)	GlycoEpitope
Echinococcus granulosus	GlycoEpitope
Oryctolagus cuniculus (rabbit)	GlyTouCan(glycome-db)
Ovis aries (sheep)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Protostomia [inference]

Ecdysozoa [inference]

Nematoda (roundworms) [inference]

Chromadorea [inference]

Rhabditida [inference]

Spirurina [inference]

Ascaridomorpha [inference]

Ascaridoidea [inference]

Toxocaridae [inference]

Toxocara [inference]

Toxocara canis (dog roundworm)

Rhabditina [inference]

Rhabditomorpha [inference]

Strongyloidea (lungworms) [inference]

Heligmosomidae [inference]

Nippostrongylus [inference]

Nippostrongylus brasiliensis

Rhabditoidea [inference]

Rhabditidae [inference]

Peloderinae [inference]

Caenorhabditis [inference]

Caenorhabditis elegans

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Calyptratae [inference]

Oestroidea [inference]

Calliphoridae (blowflies) [inference]

Chrysomyinae [inference]

Phormini [inference]

Protophormia [inference]

Protophormia terraenovae (northern blowfly)

Crustacea (crustaceans) [inference]

Multicrustacea [inference]

Malacostraca [inference]

Eumalacostraca [inference]

Peracarida [inference]

Isopoda (pill bugs, wood lice and sea slaters) [inference]

Oniscidea (pillbugs) [inference]

Crinocheta [inference]

Armadillidae [inference]

Armadillo

Spiralia [inference]

Lophotrochozoa [inference]

Platyhelminthes (flatworms) [inference]

Cestoda (tapeworms) [inference]

Eucestoda [inference]

Cyclophyllidea [inference]

Mesocestoididae [inference]

Mesocestoides [inference]

Taeniidae [inference]

Taenia [inference]

Taenia hydatigena

Echinococcus [inference]

Echinococcus granulosus group [inference]

Echinococcus granulosus

Trematoda [inference]

Digenea (flukes) [inference]

Plagiorchiida [inference]

Echinostomata [inference]

Echinostomatoidea [inference]

Fasciolidae [inference]

Fasciola [inference]

Fasciola hepatica (liver fluke)

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus [inference]

Rattus norvegicus (Norway rat)

Cricetidae [inference]

Cricetinae (hamsters) [inference]

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Chlorocebus [inference]

Chlorocebus aethiops (grivet)

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Ruminantia [inference]

Ovis aries (sheep)

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Fungi [inference]

Dikarya [inference]

Ascomycota (ascomycetes) [inference]

saccharomyceta [inference]

Saccharomycotina (true yeasts) [inference]

Saccharomycetes [inference]

Saccharomycetales [inference]

Saccharomycetaceae [inference]

Saccharomyces [inference]

Saccharomyces cerevisiae (brewer's yeast)

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Escherichia [inference]

Escherichia coli

Pseudomonadales [inference]

Pseudomonadaceae [inference]

Pseudomonas [inference]

Pseudomonas aeruginosa group [inference]

Pseudomonas aeruginosa

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Pisuviricota [inference]

Pisoniviricetes [inference]

Nidovirales [inference]

Cornidovirineae [inference]

Coronaviridae [inference]

Orthocoronavirinae [inference]

Betacoronavirus [inference]

Sarbecovirus [inference]

Severe acute respiratory syndrome-related coronavirus [inference]

Severe acute respiratory syndrome coronavirus 2

Pararnavirae [inference]

Artverviricota [inference]

Revtraviricetes [inference]

Ortervirales [inference]

Retroviridae [inference]

Orthoretrovirinae [inference]

Lentivirus [inference]

Human immunodeficiency virus 1

Primate lentivirus group [inference]

unclassified Primate lentivirus group [inference]

Human immunodeficiency virus

GlycoGene Database (GGDB)

Displaying **all 4** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
B3GNT6	UDP-GlcNAc	G57321FI	[alpha]-pNP	G00035MO	[alpha]-pNP	11821425

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC4	CMP-Neu5Ac	G57321FI	benzyl	G36123IU	benzyl	11062056
ST6GALNAC1	CMP-Neu5Ac	G57321FI	Ser/Thr	G36123IU	Ser/Thr	10536037
ST6GALNAC1	CMP-Neu5Ac	G57321FI	O-glycan Synthesis	G36123IU	O-glycan Synthesis
ST6GALNAC1	CMP-Neu5Ac	G57321FI	[Ala-Thr(*)-Ala]2-7	G36123IU	[Ala-Thr(*)-Ala]2-7	10536037

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GALNAC2	CMP-Neu5Ac	G57321FI	para-nitrophenol	10742600
ST6GALNAC1	CMP-Neu5Ac	G57321FI	[alpha]-Bz	10536037
ST6GALNAC3	CMP-Neu5Ac	G57321FI	Ser/Thr	10536037
ST6GALNAC2	CMP-Neu5Ac	G57321FI	Ser/Thr	10536037
ST6GAL2	CMP-Neu5Ac	G57321FI	para-nitrophenol	12603328

Core Protein

Displaying entries **1 - 10** of **819** in total

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UniProt ID	Protein Name	Reference	Source
A1A5C7	Solute carrier family 22 member 23	23584533	GlyGen
A1L4H1	Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D	23584533	GlyGen
A6NH11	Glycolipid transfer protein domain-containing protein 2	23584533	GlyGen
A6NLU5	V-set and transmembrane domain-containing protein 2B	23584533	GlyGen
C9J069	Apical junction component 1 homolog	23584533 25813380	GlyGen
C9JH25	Proline-rich transmembrane protein 4	23584533	GlyGen
D9N008	Epiglycanin	1125949 115878	GlyConnect
O00151	PDZ and LIM domain protein 1	23584533	GlyGen
O00220	Tumor necrosis factor receptor superfamily member 10A	23584533 25813380	GlyGen
O00238	Bone morphogenetic protein receptor type-1B	23584533	GlyGen

Pathway

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Pathway Name	Organism
E.coli O101	Escherichia coli
E.coli O103	Escherichia coli
E.coli O107	Escherichia coli
E.coli O112ab	Escherichia coli
E.coli O112ac	Escherichia coli
E.coli O116	Escherichia coli
E.coli O117	Escherichia coli
E.coli O125ab	Escherichia coli
E.coli O127	Escherichia coli
E.coli O128ab-H27	Escherichia coli

Literature

Displaying entries **191 - 200** of **2052** in total

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PubMed ID	Title	First Author	Publication Date	Source
32785915	[Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria]	Stölzel U	2020 Aug	PubChem
31987953	Purification and biochemical/biophysical characterization of two hexosaminidases from the fresh water mussel, Lamellidens corrianus	Venugopal A	2020 Apr 15	PubChem
32279507	Revealing Single-Bond Anomeric Selectivity in Carbohydrate–Protein Interactions	Saparbaev E	2020 Apr 12	PubChem
32306335	Purification and Assays of Tachylectin-5	Kawabata SI	2020	PubChem
32306351	Pleurotus cornucopiae Mycelial Lectin (PCL-M): Purification and Detection of the Activity on Mycelial Surface	Oguri S	2020	PubChem
31547886	Characterization of human norovirus binding to gut-associated bacterial ligands	Almand EA	2019 Sep 23	PubChem
31548401	The structure of the colorectal cancer-associated enzyme GalNAc-T12 reveals how nonconserved residues dictate its function	Fernandez AJ	2019 Sep 23	PubChem
31505925	Presence of N-acetylgalactosamine/galactose residues on bronchioloalveolar cells during rat postnatal development	Martins MF	2019 Sep 11	PubChem
31303442	Enhanced Potency of GalNAc-Conjugated Antisense Oligonucleotides in Hepatocellular Cancer Models	Kim Y	2019 Sep 04	PubChem
31529782	Synthesis of Monovalent N‐Acetylgalactosamine Phosphoramidite for Liver‐Targeting Oligonucleotides	Yamamoto T	2019 Sep	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
Tn-syndrome.	Berger EG	Biochim Biophys Acta	1999 Oct 8	10571017
Application of chemically desialylated and degalactosylated human glycophorin for induction and characterization of anti-Tn monoclonal antibodies.	Duk M Steuden I Duś D Radzikowski C Lisowska E	Glycoconj J	1992 Jun	1422133
Specificity of Amaranthus leucocarpus lectin.	Zenteno E Lascurain R Montaño LF Vazquez L Debray H Montreuil J	Glycoconj J	1992 Aug	1422141
Blood group Tn-active macromolecules from human carcinomas and erythrocytes: characterization of and specific reactivity with mono- and poly-clonal anti-Tn antibodies induced by various immunogens.	Springer GF Chandrasekaran EV Desai PR Tegtmeyer H	Carbohydr Res	1988 Jul 15	3056614

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