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GlyTouCan
Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
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G57321FI
Summary
- GlyTouCan ID
-
G57321FI
- IUPAC Condensed
- GalNAc(a1-
- Motifs
- Tn antigen
3D Structures
- GlycoNAVI
- G57321FI
- GlycoShape
- G57321FI
- GLYCAM
- DGalpNAca1-OH
Organisms
| Organisms | Evidence |
|---|---|
| Chlorocebus aethiops (grivet) |
Taxonomic Hierarchy
root
cellular organisms [inference]
Eukaryota (eucaryotes) [inference]
Opisthokonta [inference]
Metazoa (metazoans) [inference]
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| C1GALT1 | (not applicable) |
G57321FI
|
Ser/Thr |
G00031MO
|
Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
O-glycan Synthesis |
G36123IU
|
O-glycan Synthesis | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
Ser/Thr |
G36123IU
|
Ser/Thr | |
| B3GNT6 | UDP-GlcNAc |
G57321FI
|
[alpha]-pNP |
G00035MO
|
[alpha]-pNP |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| C1GALT1 | (not applicable) |
G57321FI
|
Ser/Thr |
G00031MO
|
Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
[Ala-Thr(*)-Ala]2-7 |
G36123IU
|
[Ala-Thr(*)-Ala]2-7 | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
O-glycan Synthesis |
G36123IU
|
O-glycan Synthesis | |
| ST6GALNAC1 | CMP-Neu5Ac |
G57321FI
|
Ser/Thr |
G36123IU
|
Ser/Thr | |
| ST6GALNAC4 | CMP-Neu5Ac |
G57321FI
|
benzyl |
G36123IU
|
benzyl |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Reference |
|---|---|---|---|---|
| ST8SIA6 | CMP-Neu5Ac |
G57321FI
|
||
| ST6GALNAC2 | CMP-Neu5Ac |
G57321FI
|
para-nitrophenol | |
| ST6GAL2 | CMP-Neu5Ac |
G57321FI
|
para-nitrophenol | |
| ST6GAL1 | CMP-Neu5Ac |
G57321FI
|
para-nitrophenol | |
| ST6GALNAC3 | CMP-Neu5Ac |
G57321FI
|
Ser/Thr |
KEGG BRITE Database
G00041MO
Core Protein
GlycoEpitope
- Epitope ID
- EP0021
- Epitope Name
- Tn Antigen
Pathway
| Pathway Name | Organism |
|---|---|
| E.coli O101 | Escherichia coli |
| E.coli O103 | Escherichia coli |
| E.coli O107 | Escherichia coli |
| E.coli O112ab | Escherichia coli |
| E.coli O112ac | Escherichia coli |
| E.coli O116 | Escherichia coli |
| E.coli O117 | Escherichia coli |
| E.coli O125ab | Escherichia coli |
| E.coli O127 | Escherichia coli |
| E.coli O128ab-H27 | Escherichia coli |
Sequence Descriptors
- GlycoCT
-
RES 1b:a-dgal-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
- WURCS
- WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 38348876 | A combinatorial approach for achieving CNS-selective RNAi | Ferguson CM | 2024 Feb 13 |
|
| 38227794 | Safety and Tolerability of GalNAc3-Conjugated Antisense Drugs Compared to the Same-Sequence 2′-O-Methoxyethyl-Modified Antisense Drugs: Results from an Integrated Assessment of Phase 1 Clinical Trial Data | Baker BF | 2024 Feb 01 |
|
| 39177802 | Givosiran for the Treatment of Pediatric Acute Intermittent Porphyria | Bujold KE | 2024 Aug 22 |
|
| 39126245 | O-GlcNAcylation determines the function of the key O-GalNAc glycosyltransferase C1GalT1 in bladder cancer | Jiang Y | 2024 Aug 01 |
|
| 38667801 | Chemical Synthesis of Fucosylated Chondroitin Sulfate Tetrasaccharide with Fucosyl Branch at the 6-OH of GalNAc Residue | Lv C | 2024 Apr 19 |
|
| 38479165 | Research progress on asialoglycoprotein receptor-targeted radiotracers designed for hepatic nuclear medicine imaging | Hua Y | 2024 Apr 05 |
|
| 38570436 | Cross-Reactive Polyclonal Antibodies Raised Against GalNAc-Conjugated siRNA Recognize Mostly the GalNAc Moiety | Ballman KK | 2024 Apr 03 |
|
| 38401583 | Deficiency of polypeptide N-acetylgalactosamine transferase 9 contributes to a risk for Parkinson's disease via mitochondrial dysfunctions | Peng Y | 2024 Apr |
|
| 38708485 | Recovery of chronic motor neuropathy due to acute intermittent porphyria after givosiran treatment in a young boy: a case report | Mazzoli M | 2024 Apr |
|
| 38995536 | Integrating HexNAcQuest with Glycoproteomics Data Analysis Software to Distinguish HexNAc Isomers on Peptides | Hou C | 2024 |
|
PubAnnotation
| Title | Authors | Source | Publication Date | PubMed ID |
|---|---|---|---|---|
| GALNTs: master regulators of metastasis-associated epithelial-mesenchymal transition (EMT)? |
|
Glycobiology | 2022 Jun 13 | 35312770 |
| The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors. |
|
J Biol Chem | 2017 Jul 21 | 28546425 |
| The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR. |
|
J Am Chem Soc | 2015 Oct 7 | 26366611 |
| Single molecule study of heterotypic interactions between mucins possessing the Tn cancer antigen. |
|
Glycobiology | 2015 May | 25527429 |
| Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice. |
|
J Biol Chem | 2015 Aug 14 | 26124270 |
