G57321FI

Summary
GlyTouCan ID
G57321FI
IUPAC Condensed
GalNAc(a1-
Motifs
Tn antigen
GlyConnect structure
GlyGen
ChEBI
PubChem Compound
PubChem Substance
The Human Metabolome Database
3D Structures
GlycoNAVI
G57321FI
GlycoShape
G57321FI
GLYCAM
DGalpNAca1-OH
Organisms
Taxonomic Hierarchy
GlycoGene Database (GGDB)
Displaying all 4 entries
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
B3GNT6 UDP-GlcNAc
G57321FI
[alpha]-pNP
G00035MO
[alpha]-pNP
Displaying entries 1 - 5 of 9 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Product Reducing terminal(Product) Reference
C1GALT1 (not applicable)
G57321FI
Ser/Thr
G00031MO
Ser/Thr
ST6GALNAC1 CMP-Neu5Ac
G57321FI
[Ala-Thr(*)-Ala]2-7
G36123IU
[Ala-Thr(*)-Ala]2-7
ST6GALNAC1 CMP-Neu5Ac
G57321FI
O-glycan Synthesis
G36123IU
O-glycan Synthesis
ST6GALNAC1 CMP-Neu5Ac
G57321FI
Ser/Thr
G36123IU
Ser/Thr
ST6GALNAC4 CMP-Neu5Ac
G57321FI
benzyl
G36123IU
benzyl
Displaying entries 1 - 5 of 35 in total
Gene Symbol Donor Acceptor Reducing terminal(Acceptor) Reference
ST8SIA6 CMP-Neu5Ac
G57321FI
ST6GALNAC2 CMP-Neu5Ac
G57321FI
para-nitrophenol
ST6GAL2 CMP-Neu5Ac
G57321FI
para-nitrophenol
ST6GAL1 CMP-Neu5Ac
G57321FI
para-nitrophenol
ST6GALNAC3 CMP-Neu5Ac
G57321FI
Ser/Thr
GlycoEpitope
Epitope ID
EP0021
Epitope Name
Tn Antigen
Pathway
Displaying entries 1 - 10 of 57 in total
Pathway Name Organism
E.coli O101 Escherichia coli
E.coli O103 Escherichia coli
E.coli O107 Escherichia coli
E.coli O112ab Escherichia coli
E.coli O112ac Escherichia coli
E.coli O116 Escherichia coli
E.coli O117 Escherichia coli
E.coli O125ab Escherichia coli
E.coli O127 Escherichia coli
E.coli O128ab-H27 Escherichia coli
Sequence Descriptors
GlycoCT
RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
LIN
1:1d(2+1)2n
WURCS
WURCS=2.0/1,1,0/[a2112h-1a_1-5_2*NCC/3=O]/1/
Literature
Displaying entries 41 - 50 of 2052 in total
PubMed ID Title First Author Publication Date Source
37348365 Precolumn derivatization LC-MS/MS method to simultaneous quantitation of 10 monosaccharides in rat plasma Li M 2023 Sep 20
  • PubChem
37679570 Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses Tremain AC 2023 Sep 07
  • PubChem
37897177 N-acetylgalactosamine delivery systems for RNA therapeutics: a patent perspective Zhang H 2023 Sep 02
  • PubChem
37824025 Plasma Pharmacokinetics of N-Acetylgalactosamine-Conjugated Small-Interfering Ribonucleic Acids (GalNAc-Conjugated siRNAs) Sten S 2023 Oct 12
  • PubChem
37429729 In Vivo Metabolite Profiles of an N-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and Humans Li XQ 2023 Oct
  • PubChem
37495504 [Acute intermittent porphyria: Acute flare-up resolved with givosiran] Balado González AM 2023 Nov 24
  • PubChem
37222604 The deleterious variants of N-acetylgalactosamine-6-sulfatase (GalN6S) enzyme trigger Morquio a syndrome by disrupting protein foldings Li J 2023 May 24
  • PubChem
37003277 Fitusiran prophylaxis in severe haemophilia without inhibitors Jiménez-Yuste V 2023 May
  • PubChem
36997646 Structural basis for translation inhibition by the glycosylated drosocin peptide Koller TO 2023 Mar 30
  • PubChem
36971831 Sensitive Electrochemical Sensor for Glycoprotein Detection Using a Self-Serviced-Track 3D DNA Walker and Catalytic Hairpin Assembly Enzyme-Free Signal Amplification Xu W 2023 Mar 27
  • PubChem
PubAnnotation
Displaying entries 1 - 5 of 10 in total
Title Authors Source Publication Date PubMed ID
GALNTs: master regulators of metastasis-associated epithelial-mesenchymal transition (EMT)?
  • Beaman EM
  • Carter DRF
  • Brooks SA
Glycobiology 2022 Jun 13 35312770
The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors.
  • Sato M
  • Liebschner D
  • Yamada Y
  • Matsugaki N
  • Arakawa T
  • Wills SS
  • Hattie M
  • Stubbs KA
  • Ito T
  • Senda T
  • Ashida H
  • Fushinobu S
J Biol Chem 2017 Jul 21 28546425
The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.
  • Coelho H
  • Matsushita T
  • Artigas G
  • Hinou H
  • Cañada FJ
  • Lo-Man R
  • Leclerc C
  • Cabrita EJ
  • Jiménez-Barbero J
  • Nishimura S
  • Garcia-Martín F
  • Marcelo F
J Am Chem Soc 2015 Oct 7 26366611
Single molecule study of heterotypic interactions between mucins possessing the Tn cancer antigen.
  • Haugstad KE
  • Stokke BT
  • Brewer CF
  • Gerken TA
  • Sletmoen M
Glycobiology 2015 May 25527429
Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice.
  • Song K
  • Herzog BH
  • Fu J
  • Sheng M
  • Bergstrom K
  • McDaniel JM
  • Kondo Y
  • McGee S
  • Cai X
  • Li P
  • Chen H
  • Xia L
J Biol Chem 2015 Aug 14 26124270

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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