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MIRAGE
Poly [ADP-ribose] polymerase tankyrase-2
Summary
- UniProt ID
- Q9H2K2
- Gene Symbol
- TNKS2 PARP5B TANK2 TNKL
- Gene ID
- 80351
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9H2K2
- PubChem
- Q9H2K2
- The Human Metabolome Database
- HMDBP00901
- Re-Glyco
- Q9H2K2
Annotation
- Keyword
- 3D-structure ADP-ribosylation ANK repeat Cytoplasm Glycosyltransferase Golgi apparatus Hydroxylation Membrane Metal-binding NAD Nucleotidyltransferase Nucleus Proteomics identification Reference proteome Repeat Telomere Ubl conjugation Wnt signaling pathway Zinc
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| protein polyubiquitination | ||
| protein polyubiquitination | ||
| Wnt signaling pathway |
|
|
| positive regulation of telomere maintenance via telomerase | ||
| positive regulation of telomere maintenance via telomerase |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| Golgi membrane | ||
| pericentriolar material | ||
| pericentriolar material | ||
| chromosome, telomeric region | ||
| chromosome, telomeric region |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| NAD+ poly-ADP-ribosyltransferase activity | ||
| NAD+ poly-ADP-ribosyltransferase activity | ||
| NAD+ poly-ADP-ribosyltransferase activity | ||
| NAD+ poly-ADP-ribosyltransferase activity | ||
| nucleotidyltransferase activity |
|
|
GO Hierarchy
Sequence
MSGRRCAGGGAACASAAAEAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAMPPSALPSCYKPQVLNGVRSPGATADALSSGPSSPSSLSAASSLDNLSGSFSELSSVVSSSGTEGASSLEKKEVPGVDFSITQFVRNLGLEHLMDIFEREQITLDVLVEMGHKELKEIGINAYGHRHKLIKGVERLISGQQGLNPYLTLNTSGSGTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPEGMVDG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 319 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Degradation of AXIN | Homo sapiens |
| Regulation of PTEN stability and activity | Homo sapiens |
| TCF dependent signaling in response to WNT | Homo sapiens |
| Ub-specific processing proteases | Homo sapiens |
| XAV939 stabilizes AXIN | Homo sapiens |
