GlyCosmos Portal

Agglutinin

Summary

GlyCosmos Lectin

GL_000028

Lectin Name Aliases

Organism

Ricinus communis (castor bean)

External Links

UniProt

P06750

UniLectin

P06750

CarboGrove

Annotation

Keyword: 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lectin Nucleotide-binding Plant defense Protein synthesis inhibitor Repeat Signal Toxin

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	Reference
defense response
negative regulation of translation	IEA	GO_REF

GO Hierarchy

biological process

response to stimulus [inference]

response to stress [inference]

defense response

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

regulation of protein metabolic process [inference]

regulation of translation [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

Displaying 1 entry
GO Term	Evidence Code	Reference
endoplasmic reticulum	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 4** entries
GO Term	Evidence Code	Reference
nucleotide binding
carbohydrate binding
rRNA N-glycosylase activity	IEA	GO_REF GO_REF
toxin activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

RNA glycosylase activity [inference]

rRNA N-glycosylase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA glycosylase activity [inference]

rRNA N-glycosylase activity

catalytic activity, acting on a rRNA [inference]

rRNA N-glycosylase activity

binding [inference]

carbohydrate binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

nucleoside phosphate binding [inference]

nucleotide binding

toxin activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

UniLectin

UniProt
P06750

CarboGrove

Lectin Name: Ricinus Communis Agglutinin
Common Name: RCA

Automated Analysis report (Top 10 high affinity glycans)

Array Source

CFG

Protein Source

EY Labs

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G37796OS	13124.53	801.1
G18938DW	13040.76	1367.71
G74325TG	11462.34	1594.4
G96852SM	10712.78	592.95
G88094DN	10670.36	1393.65
G24604HV	10546.41	1080.5
G83133GQ	9929.38	780.27
G28659UB	9716.71	550.54
G97894QD	9043.89	998.38
G17807LO	8915.84	440.09

GlyTouCan ID	Binding Intensity	Stdev
G19687OL	43958.62	1256.03
G18938DW	41863.58	1394.61
G35679TE	41241.15	2850.98
G90130AG	39113.17	891.97
G28659UB	38765.16	677.72
G96852SM	38352.56	3146.88
G45359RY	38310.66	3449.18
G54953LX	37800.8	462.23
G92140GK	37709.05	2134.04
G36191CD	37674.26	4205.3

GlyTouCan ID	Binding Intensity	Stdev
G97894QD	43204.98	1258.18
G35382VN	43044.59	462.39
G35679TE	42533.62	1468.28
G59122OR	42508.63	1121.21
G45359RY	42287.5	1883.44
G24504JY	42041.46	1092.88
G92140GK	41569.51	2206.72
G83133GQ	40528.83	3436.58
G28678TH	40282.87	1466.84
G74325TG	40261.67	1563.02

CarboGrove View

Array Source

ASYMN

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G91365ZQ	6685.5	144.02
G29857RC	5403.83	499.15
G75850OP	5300.5	554.64
G06969ZX	4575.33	267.59
G66937TJ	4072.83	486.73
G31010RQ	3255.17	432.85
G01935FK	2765.33	302.32
G69411IG	2565.33	646.64
G36191CD	2551.83	559.46
G30370YC	2070.67	410.74

GlyTouCan ID	Binding Intensity	Stdev
G91365ZQ	17422.17	551.01
G06969ZX	17369.33	375.8
G66937TJ	16553	366.86
G31010RQ	14997	1480.57
G01935FK	14818.5	290.2
G36191CD	14561.5	268.72
G29857RC	14479.17	1043.2
G69411IG	13381.5	2173.58
G75850OP	13187.17	332.32
G30370YC	12890.17	978.66

GlyTouCan ID	Binding Intensity	Stdev
G66937TJ	24931	704.49
G29857RC	23549.5	465.9
G01935FK	23142.67	157.92
G06969ZX	22870.33	821.93
G91365ZQ	22614.5	396.79
G36191CD	22557.33	296.22
G58896AZ	22461.17	1278.68
G69411IG	21763.17	893.08
G28663KH	21088	1280.88
G27919IH	20678.33	234.59

GlyTouCan ID	Binding Intensity	Stdev
G66937TJ	25735.83	636.65
G58896AZ	25306.67	684.19
G01935FK	25156.33	286.7
G29857RC	25107.83	151.5
G27919IH	24191.67	409.64
G45560HM	24054.83	453.97
G28663KH	23087	1572.1
G91365ZQ	22949.83	690.5
G65597BI	22704.5	834.09
G97947UQ	22323.2	240

CarboGrove View

Array Source

CFG

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G17807LO	2995.34	64.52
G37796OS	2676.87	184.74
G97249VB	2617.8	143.55
G96852SM	2516.83	121.11
G36191CD	2516.64	126
G75850OP	2282.9	192.73
G91365ZQ	2279.02	68.44
G19687OL	2277.43	205.05
G04497XO	2207.69	80.14
G74325TG	2173.09	483.44

GlyTouCan ID	Binding Intensity	Stdev
G30694RX	44635.42	2667.81
G59122OR	40263.1	2359.99
G18938DW	40179.41	4300.81
G00720XU	39411.05	992.94
G73305LV	38967.23	2736.77
G96852SM	37152.08	4900.38
G30558XQ	34630.04	3527.38
G35679TE	33902.96	2636.36
G74325TG	33557.06	1828.23
G88094DN	32867.74	1671.81

GlyTouCan ID	Binding Intensity	Stdev
G96852SM	47530.87	9152.28
G30694RX	47371.99	8851.72
G97894QD	45974.74	5916.52
G59122OR	42981.79	1148.81
G19687OL	42809.75	8823.67
G74325TG	42739.81	3460.24
G83133GQ	42036.81	2503.23
G73305LV	41671.91	2573.54
G00720XU	40959.62	669.05
G86522OD	40774.76	3780.93

GlyTouCan ID	Binding Intensity	Stdev
G00055MO	57993.02	243.94
G09921WG	56892.95	13925.19
G92140GK	47305.6	4754.2
G12637ID	46921.75	14817.53
G91257NC	46020.82	8403.18
G24604HV	45798.03	5297.76
G00720XU	45313.8	7403.75
G18320HP	45163.92	2586.1
G19687OL	44681.6	2443.25
G19687OL	44514.77	2811.14

CarboGrove View

Array Source

FeiziCLL

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G54388ZL	32765	0
G46885EU	29689	0
G41868HL	27626	0
G00594CD	27303	0
G85735NR	27146	0
G54021WX	22759	0
G78367WA	17712	0
G59901EA	17619	0
G54388ZL	16478	0
G85278ER	15918	0

CarboGrove View

Array Source

Microbial

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G27786ED	56376.5	4098.39
G26425MP	49430	2356.79
G84224TW	49079.5	8223.65
G84224TW	41735.5	7534.93
G58896AZ	40095	160.51
G08772KU	38415	1001.97
G04941YC	37443	1710.49
G78074HX	30679.5	2602.15
G26425MP	28370.5	2134.05
G00049MO	25023	351.43

GlyTouCan ID	Binding Intensity	Stdev
G27786ED	56376.5	4098.39
G26425MP	49430	2356.79
G84224TW	49079.5	8223.65
G84224TW	41735.5	7534.93
G58896AZ	40095	160.51
G08772KU	38415	1001.97
G04941YC	37443	1710.49
G78074HX	30679.5	2602.15
G26425MP	28370.5	2134.05
G00049MO	25023	351.43

CarboGrove View

Array Source

NCFG

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G73305LV	52103	1958
G59122OR	47214	1835
G00720XU	42133	1228
G75850OP	39532	3853
G19687OL	38967	2632
G83133GQ	38338	2162
G18938DW	36772	4176
G90130AG	33962	5073
G37796OS	33413	4038
G97894QD	32979	6135

GlyTouCan ID	Binding Intensity	Stdev
G00720XU	47312	1116
G73305LV	46099	1943
G90130AG	44209	1880
G75850OP	42837	3885
G19687OL	41266	2216
G46055MA	41227	2512
G36859SD	39741	2587
G84467IZ	37608	4594
G19687OL	37116	3829
G28678TH	36533	2486

CarboGrove View

Array Source

NGGM-TM

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G48059CD	316	78.77
G86522OD	154	70.11
G45827GY	100.5	32.51
G70851FQ	70	11.34
G42553JB	30.25	30.21
G60956VN	22.5	7.59
G98602UY	18	45.09
G48600JD	16.5	8.5
G88766TD	15.5	15.8
G06031DD	11.5	25.09

GlyTouCan ID	Binding Intensity	Stdev
G48059CD	12842.25	658.84
G86522OD	10226.5	1202.33
G70851FQ	8255	833.15
G45827GY	256.75	53.09
G60956VN	252.5	25.28
G65112QB	45.5	30.36
G42553JB	35.75	12.71
G41473XU	34.75	18.87
G48600JD	31.75	16.21
G24499XE	24	28.08

GlyTouCan ID	Binding Intensity	Stdev
G48059CD	65420	32.27
G86522OD	63110	713.84
G70851FQ	35841.5	5678.7
G69893KP	6274	590.81
G60956VN	4616.25	183.12
G45827GY	1301.5	155.55
G68856EP	966.5	171.15
G01685IB	461.75	62.65
G41473XU	236.5	65.25
G06000DZ	227.25	33.68

CarboGrove View

Array Source

PolyLacNAc

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G77285LE	24633	1435
G65223RT	24486	1677
G96841VW	21793	834
G84034JH	21044	1005
G58896AZ	7426	968
G84224TW	5501	394
G72002FC	2136	413
G32061UE	4	1
G91404LJ	4	3
G91560NT	3	1

CarboGrove View

Array Source

ZBiotech

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G37591JC	25932	515.68
G58236FD	19365.33	808.33
G46998LN	18465.33	2261.49
G73866ZM	16276	857.23
G95306KD	8199.83	577.16
G98223HN	8059.17	1268.3
G93164KQ	7825.33	1556.26
G01670UQ	5871.67	896.66
G62112AO	4114.83	214.32
G31865AG	1653.83	449.19

CarboGrove View

Array Source

ZBiotech

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G72356JA	52390.38	417.14
G86522OD	50905.38	650.72
G58236FD	50876.63	961.34
G51274LI	50675.13	1392.16
G37591JC	50607.63	1222.77
G67915MO	50565.88	345.53
G01670UQ	50177.88	1796.18
G36859SD	50025.75	598.41
G63480NF	50012.38	1068.03
G14854WL	49249	321.29

CarboGrove View

Array Source

ZBiotech

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G24604HV	21104.67	0
G66741YQ	20566.17	0
G73866ZM	20417.67	0
G86522OD	18830.34	0
G44747CU	17097.84	0
G29024OJ	15782	0
G48059CD	12850	0
G93164KQ	11573	0
G00068MO	10216	0
G61730RY	8766	0

CarboGrove View

Array Source

ZBiotech

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G48059CD	3410.67	353.33
G45827GY	254.25	48.21
G26384MA	3.92	4.69
G48740SL	3.84	3.01
G87727XV	3.25	1.8
G28604UG	2.84	4.32
G41759HA	2.5	4.08
G83916HL	2.5	1.75
G28800UK	2.17	2.61
G93468NI	2	2.04

CarboGrove View

Array Source

ZBiotech

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G48059CD	37654.5	88.39
G72506RN	34426.25	551.19
G51331BY	20338	700.04
G69893KP	11633.5	693.67
G09376MR	7338.25	262.69
G45827GY	3993.75	52.68
G74621DY	1622.5	137.89
G55205ZV	470	220.62
G01187XC	440.25	157.33
G48027TR	309.5	53.03

GlyTouCan ID	Binding Intensity	Stdev
G48059CD	10630	1472.28
G72506RN	8049.84	1568.05
G51331BY	2983.17	278.26
G69893KP	190	133.54
G45827GY	171.67	10.26
G74621DY	99.34	43.98
G09376MR	59.5	7.08
G07982RO	44.84	5.62
G39211DH	33.67	22.27
G49963IQ	24.34	13.8

CarboGrove View

Array Source

ZBiotech

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G69508SI	46011	1929.32
G74553FZ	35566.33	391.65
G48059CD	26966.33	1157.04
G58274PS	26569	797.94
G40155OZ	21622.33	1093.04
G09962WA	21084	1986.45
G69893KP	19020.67	938.96
G72506RN	17721.33	1288.16
G72506RN	17100	2589.24
G51119AC	13263.67	95.5

CarboGrove View

Array Source

ZBiotech

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G65223RT	26573.92	603.1
G84034JH	25051.42	1769.03
G77285LE	24921.42	1029.57
G58896AZ	24493.75	641.78
G84224TW	24185.67	286.05
G40491DT	23513.33	1069.84
G96841VW	22632.75	1278.75
G72002FC	19324.67	825.42
G91404LJ	4.5	5.79
G70874WW	1.33	3.08

CarboGrove View

Array Source

ZBiotech

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G37591JC	19382.25	2439.87
G66741YQ	15304.25	204
G86386QT	11544.75	257.03
G58236FD	10956	442.65
G01670UQ	10247	902.27
G73866ZM	8682.75	2029.04
G13773HT	8469.5	1725.34
G44747CU	8014.75	722.31
G44754DF	6745.5	358.5
G10106TL	6702.75	1294.36

CarboGrove View

Array Source

ZBiotech

Protein Source

Vector

Concentration (ug/mL)

GlyTouCan ID	Binding Intensity	Stdev
G68386YJ	11648.83	2241.53
G16404NW	9709.5	257.26
G64973KT	8131.83	1266.5
G86678MP	6275	114.18
G61730RY	5098.5	188.54
G77477NL	4267	597.7
G64018QW	3903.83	176.12
G69733HD	3896	28.62
G32723SL	3523	442.5
G31672PK	3279.83	250.11

CarboGrove View

CarboGrove is populated with the results from 35 types of glycan arrays, 13 glycan families, 5 experimental methods, and 19 laboratories or companies by processing and interpreting data from various types of glycan arrays.

PDB

1RZO

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

CarboGrove

PDB

International Collaboration

Acknowledgements

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

CarboGrove

0.1

1

10

0.1

1

10

50

0.1

1

10

100

1X

20

20

1

10

0.1

1

10

10

2

2

10

2

2

2

2

2

2

2

PDB

International Collaboration

Acknowledgements