GlyCosmos Portal

Submissions

G00031MO

Summary

GlyTouCan ID: G00031MO
IUPAC Condensed: Gal(b1-3)GalNAc(a1-
Motifs: O-Glycan core 1 T antigen TF antigen
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 383.14

External Links

GlyConnect structure

1947

GlyGen

G00031MO

ChEBI

61820

PubChem Compound

5288347

PubChem Substance

252294787

CarbBank

3D Structures

GLYCAM: DGalpb1-3DGalpNAca1-OH

GlycoShape

G00031MO

Displaying 1 entry
Archetype	α	β
G00032MO	G00031MO	G01534TU

Organisms

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Organisms	Evidence
Gadus	GlyTouCan(glycome-db)
Cricetulus griseus (Chinese hamster)	GlyTouCan(glycome-db)
Mus musculus (house mouse)	GlyConnectStructure GlyTouCan(glycome-db) GlycoEpitope
Bos taurus (domestic cattle)	GlyTouCan(glycome-db)
Rattus	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

Viruses [inference]

Riboviria [inference]

Orthornavirae [inference]

Pisuviricota [inference]

Pisoniviricetes [inference]

Nidovirales [inference]

Cornidovirineae [inference]

Coronaviridae [inference]

Orthocoronavirinae [inference]

Betacoronavirus [inference]

Sarbecovirus [inference]

Severe acute respiratory syndrome-related coronavirus [inference]

Severe acute respiratory syndrome coronavirus 2

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Euteleosteomorpha [inference]

Neoteleostei [inference]

Eurypterygia [inference]

Ctenosquamata [inference]

Acanthomorphata [inference]

Paracanthopterygii [inference]

Zeiogadaria [inference]

Gadariae [inference]

Gadiformes (cods and others) [inference]

Gadoidei [inference]

Gadidae (cods) [inference]

Gadus

Gadus chalcogrammus (walleye pollock)

Pollachius [inference]

Pollachius pollachius (pollack)

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Euarchontoglires [inference]

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Macaca (macaques) [inference]

Macaca mulatta (Rhesus monkey)

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Rattus norvegicus (Norway rat)

Cricetidae [inference]

Cricetinae (hamsters) [inference]

Cricetulus [inference]

Cricetulus griseus (Chinese hamster)

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig) [inference]

Sus scrofa domesticus (domestic pig)

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Carnivora (carnivores) [inference]

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Protostomia [inference]

Ecdysozoa [inference]

Panarthropoda [inference]

Arthropoda (arthropods) [inference]

Mandibulata [inference]

Pancrustacea [inference]

Hexapoda (hexapods) [inference]

Insecta (insects) [inference]

Dicondylia [inference]

Pterygota (winged insects) [inference]

Neoptera [inference]

Endopterygota [inference]

Diptera (flies) [inference]

Brachycera [inference]

Muscomorpha [inference]

Eremoneura [inference]

Cyclorrhapha [inference]

Schizophora [inference]

Acalyptratae [inference]

Ephydroidea [inference]

Drosophilidae (pomace flies) [inference]

Drosophilinae [inference]

Drosophilini [inference]

Drosophila (fruit flies) [inference]

Sophophora [inference]

melanogaster group [inference]

melanogaster subgroup [inference]

Drosophila melanogaster (fruit fly)

Bacteria (eubacteria) [inference]

Pseudomonadota [inference]

Gammaproteobacteria [inference]

Enterobacterales [inference]

Enterobacteriaceae [inference]

Shigella [inference]

Shigella dysenteriae

FCB group [inference]

Bacteroidota/Chlorobiota group [inference]

Bacteroidota [inference]

Bacteroidia [inference]

Bacteroidales [inference]

Bacteroidaceae [inference]

Bacteroides [inference]

Bacteroides ovatus

GlycoGene Database (GGDB)

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST6GALNAC1	CMP-Neu5Ac	G00031MO	Ser/Thr	G56682BC	Ser/Thr	10536037
ST3GAL2	CMP-Neu5Ac	G00031MO	R	G65562ZE	R	9266697
ST6GALNAC2	CMP-Neu5Ac	G00031MO	Ser/Thr	G56682BC	Ser/Thr	10742600
ST3GAL4	CMP-Neu5Ac	G00031MO	free	G65562ZE	free	8288606

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
C1GALT1	(not applicable)	G57321FI	Ser/Thr	G00031MO	Ser/Thr	11677243
ST3GAL3	CMP-Neu5Ac	G00031MO	free	G65562ZE	free	8288606
ST6GALNAC1	CMP-Neu5Ac	G00031MO	Ser/Thr	G56682BC	Ser/Thr	10536037
ST3GAL2	CMP-Neu5Ac	G00031MO	R	G65562ZE	R	9266697
ST6GALNAC1	CMP-Neu5Ac	G00031MO	O-glycan Synthesis	G56682BC	O-glycan Synthesis

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Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST6GAL2	CMP-Neu5Ac	G00031MO	free	12235148
ST6GALNAC4	CMP-Neu5Ac	G00031MO	benzyl	11062056
ST6GALNAC3	CMP-Neu5Ac	G00031MO	Ser/Thr	10536037
ST3GAL3	CMP-Neu5Ac	G00031MO	Antifreeze glycoprotein	8288606
ST3GAL6	CMP-Neu5Ac	G00031MO	free	10206952

KEGG BRITE Database

KEGG ID

Enzyme

References

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05908	2.4.1.122	G57321FI	G00031MO
R12704	2.4.3.3	G00031MO	G28694FA
R05912	2.4.1.102	G00031MO	G00033MO
R05913	2.4.3.4	G00031MO	G65562ZE

Core Protein

Displaying entries **21 - 30** of 50 in total

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UniProt ID	Protein Name	Reference	Source
P08575	Receptor-type tyrosine-protein phosphatase C	8122360 9492296	GlyGen GlyConnect
P0DN86	Choriogonadotropin subunit beta 3	1374031 1820200 1967025 3335536 468798 9449027	GlyGen GlyConnect GlyConnect
P0DTC2	Spike glycoprotein	33806155 33871970	GlyGen GlyConnect GlyConnect GlyConnect GlyConnect
P10645	Chromogranin-A	9852066	GlyGen GlyConnect
P10761	Zona pellucida sperm-binding protein 3	14673092	GlyGen GlyConnect
P11279	Lysosome-associated membrane glycoprotein 1	8323299	GlyGen GlyConnect
P12259	Coagulation factor V	32310329	GlyGen GlyConnect
P13473	Lysosome-associated membrane glycoprotein 2	8323299	GlyGen GlyConnect
P14780	Matrix metalloproteinase-9	11123894	GlyGen GlyConnect
P15941	Mucin-1	11445551 8969192 9530955	GlyGen GlyConnect GlyConnect GlyConnect GlyConnect GlyConnect GlyConnect GlyConnect

GlycoEpitope

Epitope ID: EP0020

Pathway

Displaying **all 8** entries
Pathway Name	Organism
E.coli O107	Escherichia coli
E.coli O117	Escherichia coli
E.coli O185	Escherichia coli
E.coli O5ab	Escherichia coli
E.coli O5ac	Escherichia coli
E.coli O70	Escherichia coli
E.coli O71	Escherichia coli
E.coli O83	Escherichia coli

Sequence Descriptors

GlycoCT

RES
1b:a-dgal-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
LIN
1:1d(2+1)2n
2:1o(3+1)3d

WURCS

WURCS=2.0/2,2,1/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5]/1-2/a3-b1

Literature

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PubMed ID	Title	First Author	Publication Date	Source
14673092	Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans	Dell A	2003 Dec 12	GlyGen PubChem
12235148	Characterization of the second type of human beta-galactoside alpha 2,6-sialyltransferase (ST6Gal II), which sialylates Galbeta 1,4GlcNAc structures on oligosaccharides preferentially. Genomic analysis of human sialyltransferase genes	Takashima S	2002 Nov 29	PubChem
12000758	Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation	Muller S	2002 Jul 19	GlyGen
11677243	Cloning and expression of human core 1 beta1,3-galactosyltransferase	Ju T	2002 Jan 04	PubChem
12206779	Crystal Structure of the Jacalin–T-antigen Complex and a Comparative Study of Lectin–T-antigen Complexes	Jeyaprakash AA	2002 Aug 23	PubChem
11821425	Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans	Iwai T	2002 Apr 12	PubChem
11501845	Expression of mucin-associated carbohydrate core antigens in esophageal squamous cell carcinomas	Flucke U	2001 May-Jun	GlyGen GlycoEpitope
11396208	Immunohistochemical expression of T, Tn and sialyl-Tn antigens and clinical outcome in human breast carcinoma	Imai J	2001 Mar-Apr	GlyGen GlycoEpitope
11445551	In vivo glycosylation of mucin tandem repeats	Silverman HS	2001 Jun	GlyGen PubChem
11323440	Molecular cloning and expression of a novel human beta-Gal-3-O-sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans	Suzuki A	2001 Jun 29	PubChem

PubAnnotation

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Title	Authors	Source	Publication Date	PubMed ID
An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates.	Eckhart W Hutchinson MA Hunter T	Cell	1979 Dec	229973
Tumor antigens induced by nontransforming mutants of polyoma virus.	Silver J Schaffhausen B Benjamin T	Cell	1978 Oct	214241
Mapping of early SV40-specific functions by microinjection of different early viral DNA fragments.	Mueller C Graessmann A Graessmann M	Cell	1978 Oct	214244
Altered metabolism of heparan sulfate in simian virus 40 transformed cloned mouse cells.	Winterbourne DJ Mora PT	J Biol Chem	1978 Jul 25	209027

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements