G57321FI
| Organisms | Evidence | 
|---|---|
| Ovis aries (sheep) | |
| Cricetulus griseus (Chinese hamster) | |
| Mus musculus (house mouse) | |
| Bos taurus (domestic cattle) | |
| Escherichia coli | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference | 
|---|---|---|---|---|---|---|
| C1GALT1 | (not applicable) | 
                          
                             | 
                    Ser/Thr | 
                          
                             | 
                    Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    Ser/Thr | 
                          
                             | 
                    Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    O-glycan Synthesis | 
                          
                             | 
                    O-glycan Synthesis | |
| B3GNT6 | UDP-GlcNAc | 
                          
                             | 
                    [alpha]-pNP | 
                          
                             | 
                    [alpha]-pNP | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference | 
|---|---|---|---|---|---|---|
| C1GALT1 | (not applicable) | 
                          
                             | 
                    Ser/Thr | 
                          
                             | 
                    Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    Ser/Thr | 
                          
                             | 
                    Ser/Thr | |
| ST6GALNAC4 | CMP-Neu5Ac | 
                          
                             | 
                    benzyl | 
                          
                             | 
                    benzyl | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    O-glycan Synthesis | 
                          
                             | 
                    O-glycan Synthesis | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    [Ala-Thr(*)-Ala]2-7 | 
                          
                             | 
                    [Ala-Thr(*)-Ala]2-7 | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Reference | 
|---|---|---|---|---|
| ST6GALNAC3 | CMP-Neu5Ac | 
                          
                             | 
                    Ser/Thr | |
| ST6GAL2 | CMP-Neu5Ac | 
                          
                             | 
                    para-nitrophenol | |
| ST6GALNAC2 | CMP-Neu5Ac | 
                          
                             | 
                    benzyl | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    [alpha]-Bz | |
| ST6GALNAC2 | CMP-Neu5Ac | 
                          
                             | 
                    Ser/Thr | 
| UniProt ID | Protein Name | Reference | Source | 
|---|---|---|---|
| Q9Y624 | Junctional adhesion molecule A | ||
| Q9Y625 | Glypican-6 | ||
| Q9Y653 | Adhesion G-protein coupled receptor G1 | ||
| Q9Y662 | Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 | ||
| Q9Y6C2 | EMILIN-1 | ||
| Q9Y6I9 | Testis-expressed protein 264 | ||
| Q9Y6L7 | Tolloid-like protein 2 | ||
| Q9Y6M5 | Proton-coupled zinc antiporter SLC30A1 | ||
| Q9Y6N7 | Roundabout homolog 1 | 
| Pathway Name | Organism | 
|---|---|
| Lectin pathway of complement activation | Bos taurus | 
| Lectin pathway of complement activation | Rattus norvegicus | 
| Lectin pathway of complement activation | Mus musculus | 
| Lectin pathway of complement activation | Homo sapiens | 
| Lectin pathway of complement activation | Xenopus tropicalis | 
| Lectin pathway of complement activation | Gallus gallus | 
| Lectin pathway of complement activation | Canis familiaris | 
RES 1b:a-dgal-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
| PubMed ID | Title | First Author | Publication Date | Source | 
|---|---|---|---|---|
| 38522000 | Model‐based meta‐analysis to quantify the effects of short interfering <scp>RNA</scp> therapeutics on hepatitis B surface antigen turnover in hepatitis B‐infected mice | Sandra L | 2024 Mar 24 | 
                  
  | 
          
| 38204163 | Application of improved GalNAc conjugation in development of cost-effective siRNA therapies targeting cardiovascular diseases | Li Q | 2024 Mar 06 | 
                  
  | 
          
| 38416819 | An unusual dual sugar-binding lectin domain controls the substrate specificity of a mucin-type O-glycosyltransferase | Collette AM | 2024 Mar | 
                  
  | 
          
| 38860868 | Incorporation of Intracellular NanoSIMS Tracers to Oligonucleotide Conjugates via Strain Promoted Sydnone–Alkyne Cycloaddition | Lincy-Bianchi L | 2024 Jun 11 | 
                  
  | 
          
| 38044204 | A randomized, placebo-controlled study of givosiran in patients with acute hepatic porphyrias (ENVISION): Final (36-month) analysis of the Taiwan Cohort | Lee M | 2024 Jun | 
                  
  | 
          
| 38993155 | A GalNAc-modified CaCO3 nano-immunomodulator for targeted and responsive immunotherapy against orthotopic liver cancer | Li Y | 2024 Jul 30 | 
                  
  | 
          
| 38795858 | Bifunctional glycosphingolipid (GSL) probes to investigate GSL-interacting proteins in cell membranes | Kundu S | 2024 Jul | 
                  
  | 
          
| 38172637 | Host genetic regulation of human gut microbial structural variation | Zhernakova DV | 2024 Jan 03 | 
                  
  | 
          
| 38409587 | RNA interference in the era of nucleic acid therapeutics | Jadhav V | 2024 Feb 26 | 
                  
  | 
          
| 38535445 | Cloning and Characterization of a Novel N-Acetyl-D-galactosamine-4-O-sulfate Sulfatase, SulA1, from a Marine Arthrobacter Strain | Christensen MD | 2024 Feb 23 | 
                  
  | 
          
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: August 4, 2025