G57321FI
| Organisms | Evidence | 
|---|---|
| Ovis aries (sheep) | |
| Cricetulus griseus (Chinese hamster) | |
| Mus musculus (house mouse) | |
| Bos taurus (domestic cattle) | |
| Escherichia coli | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference | 
|---|---|---|---|---|---|---|
| C1GALT1 | (not applicable) | 
                          
                             | 
                    Ser/Thr | 
                          
                             | 
                    Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    Ser/Thr | 
                          
                             | 
                    Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    O-glycan Synthesis | 
                          
                             | 
                    O-glycan Synthesis | |
| B3GNT6 | UDP-GlcNAc | 
                          
                             | 
                    [alpha]-pNP | 
                          
                             | 
                    [alpha]-pNP | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference | 
|---|---|---|---|---|---|---|
| C1GALT1 | (not applicable) | 
                          
                             | 
                    Ser/Thr | 
                          
                             | 
                    Ser/Thr | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    Ser/Thr | 
                          
                             | 
                    Ser/Thr | |
| ST6GALNAC4 | CMP-Neu5Ac | 
                          
                             | 
                    benzyl | 
                          
                             | 
                    benzyl | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    O-glycan Synthesis | 
                          
                             | 
                    O-glycan Synthesis | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    [Ala-Thr(*)-Ala]2-7 | 
                          
                             | 
                    [Ala-Thr(*)-Ala]2-7 | 
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Reference | 
|---|---|---|---|---|
| ST6GALNAC3 | CMP-Neu5Ac | 
                          
                             | 
                    Ser/Thr | |
| ST6GAL2 | CMP-Neu5Ac | 
                          
                             | 
                    para-nitrophenol | |
| ST6GALNAC2 | CMP-Neu5Ac | 
                          
                             | 
                    benzyl | |
| ST6GALNAC1 | CMP-Neu5Ac | 
                          
                             | 
                    [alpha]-Bz | |
| ST6GALNAC2 | CMP-Neu5Ac | 
                          
                             | 
                    Ser/Thr | 
| UniProt ID | Protein Name | Reference | Source | 
|---|---|---|---|
| Q9Y624 | Junctional adhesion molecule A | ||
| Q9Y625 | Glypican-6 | ||
| Q9Y653 | Adhesion G-protein coupled receptor G1 | ||
| Q9Y662 | Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 | ||
| Q9Y6C2 | EMILIN-1 | ||
| Q9Y6I9 | Testis-expressed protein 264 | ||
| Q9Y6L7 | Tolloid-like protein 2 | ||
| Q9Y6M5 | Proton-coupled zinc antiporter SLC30A1 | ||
| Q9Y6N7 | Roundabout homolog 1 | 
| Pathway Name | Organism | 
|---|---|
| Lectin pathway of complement activation | Bos taurus | 
| Lectin pathway of complement activation | Rattus norvegicus | 
| Lectin pathway of complement activation | Mus musculus | 
| Lectin pathway of complement activation | Homo sapiens | 
| Lectin pathway of complement activation | Xenopus tropicalis | 
| Lectin pathway of complement activation | Gallus gallus | 
| Lectin pathway of complement activation | Canis familiaris | 
RES 1b:a-dgal-HEX-1:5 2s:n-acetyl LIN 1:1d(2+1)2n
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| 37348365 | Precolumn derivatization LC-MS/MS method to simultaneous quantitation of 10 monosaccharides in rat plasma | Li M | 2023 Sep 20 | 
                  
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| 37679570 | Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses | Tremain AC | 2023 Sep 07 | 
                  
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| 37897177 | N-acetylgalactosamine delivery systems for RNA therapeutics: a patent perspective | Zhang H | 2023 Sep 02 | 
                  
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| 37824025 | Plasma Pharmacokinetics of N-Acetylgalactosamine-Conjugated Small-Interfering Ribonucleic Acids (GalNAc-Conjugated siRNAs) | Sten S | 2023 Oct 12 | 
                  
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| 37429729 | In Vivo Metabolite Profiles of an N-Acetylgalactosamine–Conjugated Antisense Oligonucleotide AZD8233 Using Liquid Chromatography High-Resolution Mass Spectrometry: A Cross-Species Comparison in Animals and Humans | Li XQ | 2023 Oct | 
                  
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| 37495504 | [Acute intermittent porphyria: Acute flare-up resolved with givosiran] | Balado González AM | 2023 Nov 24 | 
                  
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| 37222604 | The deleterious variants of N-acetylgalactosamine-6-sulfatase (GalN6S) enzyme trigger Morquio a syndrome by disrupting protein foldings | Li J | 2023 May 24 | 
                  
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| 37003277 | Fitusiran prophylaxis in severe haemophilia without inhibitors | Jiménez-Yuste V | 2023 May | 
                  
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| 36997646 | Structural basis for translation inhibition by the glycosylated drosocin peptide | Koller TO | 2023 Mar 30 | 
                  
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| 36971831 | Sensitive Electrochemical Sensor for Glycoprotein Detection Using a Self-Serviced-Track 3D DNA Walker and Catalytic Hairpin Assembly Enzyme-Free Signal Amplification | Xu W | 2023 Mar 27 | 
                  
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: August 4, 2025