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Glycan Structure Repository
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Repository for lectin-assisted multimodality data
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G65562ZE
Summary
- GlyTouCan ID
-
G65562ZE
- IUPAC Condensed
- Neu5Ac(a2-3)Gal(b1-3)GalNAc(a1-
- Motifs
- Sialyl T antigen
- Subsumption Level
- Fully-defined saccharide
- Monoisotopic Mass
- 674.24
External Links
- GlyConnect structure
- GlyGen
- ChEBI
- PubChem Compound
- PubChem Substance
- CarbBank
3D Structures
G72008IY
G02684WR
Organisms
| Organisms | Evidence |
|---|---|
| Cricetulus griseus (Chinese hamster) | |
| Mus musculus (house mouse) | |
| Bos taurus (domestic cattle) | |
| Rattus norvegicus (Norway rat) | |
| Homo sapiens (human) |
Taxonomic Hierarchy
root
cellular organisms [inference]
Eukaryota (eucaryotes) [inference]
GlycoGene Database (GGDB)
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| ST6GALNAC1 | CMP-Neu5Ac |
G65562ZE
|
Ser/Thr |
G01614ZM
|
Ser/Thr | |
| ST6GALNAC3 | CMP-Neu5Ac |
G65562ZE
|
Ser/Thr |
G01614ZM
|
Ser/Thr | |
| ST3GAL2 | CMP-Neu5Ac |
G00031MO
|
R |
G65562ZE
|
R | |
| ST6GALNAC4 | CMP-Neu5Ac |
G65562ZE
|
Ser/Thr |
G01614ZM
|
Ser/Thr | |
| ST3GAL4 | CMP-Neu5Ac |
G00031MO
|
free |
G65562ZE
|
free |
| Gene Symbol | Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|---|
| ST6GALNAC4 | CMP-Neu5Ac |
G65562ZE
|
benzyl |
G01614ZM
|
benzyl | |
| ST3GAL1 | CMP-Neu5Ac |
G00031MO
|
free |
G65562ZE
|
free | |
| ST3GAL4 | CMP-Neu5Ac |
G00031MO
|
free |
G65562ZE
|
free | |
| ST6GALNAC4 | CMP-Neu5Ac |
G65562ZE
|
R |
G01614ZM
|
R | |
| ST6GALNAC2 | CMP-Neu5Ac |
G65562ZE
|
Ser/Thr |
G01614ZM
|
Ser/Thr |
KEGG BRITE Database
Core Protein
| UniProt ID | Protein Name | Reference | Source |
|---|---|---|---|
| P02724 | Glycophorin-A | ||
| P02727 | Glycophorin-A | ||
| P02765 | Alpha-2-HS-glycoprotein | ||
| P02774 | Vitamin D-binding protein | ||
| P02784 | Seminal plasma protein PDC-109 | ||
| P02787 | Serotransferrin | ||
| P03395 | Envelope glycoprotein (Fragment) | ||
| P03415 | Membrane protein | ||
| P04278 | Sex hormone-binding globulin | ||
| P04921 | Glycophorin-C |
GlycomeAtlas
Tissues in which this glycan is expressed are highlighted in yellow.
- Danio rerio
Literature
- Tissue
-
- heart
- intestine
- liver
- Reference
- Yamakawa N et al. Systems glycomics of adult zebrafish identifies organ-specific sialylation and glycosylation patterns. Nat Commun. 2018;9(1):4647. Published 2018 Nov 7. doi:10.1038/s41467-018-06950-3
- DOI
- 10.1038/s41467-018-06950-3
Localization sites organized by hierarchy by Uber-anatomy ontology (UBERON)
Sequence Descriptors
- GlycoCT
-
RES 1b:a-dgal-HEX-1:5 2s:n-acetyl 3b:b-dgal-HEX-1:5 4b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d 5s:n-acetyl LIN 1:1d(2+1)2n 2:1o(3+1)3d 3:3o(3+2)4d 4:4d(5+1)5n
- WURCS
- WURCS=2.0/3,3,2/[a2112h-1a_1-5_2*NCC/3=O][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3/a3-b1_b3-c2
Literature
| PubMed ID | Title | First Author | Publication Date | Source |
|---|---|---|---|---|
| 12678917 | Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain | Montiel MD | 2003 Jul 15 |
|
| 12000758 | Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation | Muller S | 2002 Jul 19 |
|
| 11323440 | Molecular cloning and expression of a novel human beta-Gal-3-O-sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans | Suzuki A | 2001 Jun 29 |
|
| 11294842 | Structural elucidation of the N- and O-glycans of human apolipoprotein(a): role of o-glycans in conferring protease resistance | Garner B | 2001 Jun 22 |
|
| 10970796 | Identification of transient glycosylation alterations of sialylated mucin oligosaccharides during infection by the rat intestinal parasite Nippostrongylus brasiliensis | Karlsson NG | 2000 Sep 15 |
|
| 11062056 | Cloning, expression and gene organization of a human Neu5Ac alpha 2-3Gal beta 1-3GalNAc alpha 2,6-sialyltransferase: hST6GalNAcIV | Harduin-Lepers A | 2000 Nov 15 |
|
| 10861392 | Metabolic shifts do not influence the glycosylation patterns of a recombinant fusion protein expressed in BHK cells | Cruz HJ | 2000 Jul 20 |
|
| 11123894 | O-Glycan Analysis of Natural Human Neutrophil Gelatinase B Using a Combination of Normal Phase- HPLC and Online Tandem Mass Spectrometry: Implications for the Domain Organization of the Enzyme | Mattu TS | 2000 Dec 01 |
|
| 10742600 | Molecular cloning and functional expression of human ST6GalNAc II. Molecular expression in various human cultured cells | Samyn-Petit B | 2000 Apr 06 |
|
| 10536037 | Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens | Ikehara Y | 1999 Nov 01 |
|
