GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (10109) Glycans (5831) Glycoproteins (15837) Lectins (297) Pathways (2074)

Displaying entries **301 - 325** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	GlyTouCan ID
Alkylating DNA damage induced by chemotherapeutic drugs				G44151BN
Cyclin A/B1/B2 associated events during G2/M transition	CDK-activating kinase assembly factor MAT1 Cyclin-A1 Cyclin-A2 Cyclin-H Cyclin-dependent kinase 1 Cyclin-dependent kinase 2 Cyclin-dependent kinase 7 Exportin-1 Forkhead box protein M1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Leucine carboxyl methyltransferase 1 M-phase inducer phosphatase 1 M-phase inducer phosphatase 2 M-phase inducer phosphatase 3 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Protein phosphatase methylesterase 1 Serine/threonine-protein kinase PLK1 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta Wee1-like protein kinase	O14980 O95067 P06493 P14635 P20248 P24941 P30153 P30154 P30291 P30304 P30305 P30307 P50613 P51946 P51948 P53350 P62714 P63151 P67775 P78396 Q08050 Q99640 Q9UIC8 Q9Y570 Q9Y5P8	CAK CAK1 CAP35 CCN1 CCNA CCNA1 CCNA2 CCNB CCNB1 CCNB2 CCNH CDC2 CDC25A CDC25B CDC25C CDC25HU2 CDC28A CDK1 CDK2 CDK7 CDKN1 CDKN2 CDKN7 CRM1 FKHL16 FOXM1 HFH11 LCMT LCMT1 MAT1 MNAT1 MO15 MPP2 MYT1 P34CDC2 PKMYT1 PLK PLK1 PME1 PPME1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R3B PPP2R3L RNF66 STK1 WEE1 WIN XPO1
Processive synthesis on the lagging strand	DNA ligase 1 DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA primase large subunit DNA primase small subunit Proliferating cell nuclear antigen	P09884 P12004 P18858 P28340 P49005 P49642 P49643 Q14181 Q15054 Q9HCU8	KIAA0039 LIG1 PCNA POLA POLA1 POLA2 POLD POLD1 POLD2 POLD3 POLD4 POLDS PRIM1 PRIM2 PRIM2A
Formation of the Early Elongation Complex	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 P13984 P18074 P18615 P19387 P19388 P19447 P24928 P30876 P32780 P35269 P36954 P50613 P51946 P51948 P52298 P52434 P52435 P53803 P61218 P62487 P62875 P63272 Q09161 Q13888 Q13889 Q6ZYL4 Q8IXH7 Q8WX92 Q92759 Q9H3P2 Q9Y5B0	BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CBP20 CBP80 CCNH CDK7 CDKN7 COBRA1 CTDP1 ERCC2 ERCC3 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA1182 MAT1 MNAT1 MO15 NCBP NCBP1 NCBP2 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RNF66 RPB7 SPT4H SPT5 SPT5H STK1 SUPT4H SUPT4H1 SUPT5H TH1 TH1L TTDA WHSC2 XPB XPBC XPD XPDC
RHO GTPases Activate WASPs and WAVEs	Abl interactor 1 Abl interactor 2 Actin nucleation-promoting factor WAS Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 BAR/IMD domain-containing adapter protein 2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 Focal adhesion kinase 1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 NCK-interacting protein with SH3 domain Nck-associated protein 1-like Nck-associated protein 1 Protein BRICK1 Ras-related C3 botulinum toxin substrate 1 SH2/SH3 adapter protein NCK1 Tyrosine-protein kinase ABL1 Tyrosine-protein kinase BTK WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 2 WAS/WASL-interacting protein family member 3	A6NGB9 O00401 O15143 O15144 O15145 O15511 O43516 P00519 P16333 P27361 P28482 P42768 P55160 P59998 P60709 P60953 P61158 P61160 P63000 P63261 Q05397 Q06187 Q7L576 Q8IZP0 Q8TF74 Q8WUW1 Q92558 Q92747 Q96F07 Q9NYB9 Q9NZQ3 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y6W5	ABI1 ABI2 ABL ABL1 ACTB ACTG ACTG1 ACTR2 ACTR3 AF3P21 AGMX1 ARC16 ARC20 ARC21 ARC34 ARC41 ARGBPIA ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ATK BAIAP2 BPK BRK1 BTK C3orf10 CDC42 CR16 CYFIP1 CYFIP2 ERK1 ERK2 FAK FAK1 HEM1 HEM2 IMD2 JTK7 KIAA0068 KIAA0269 KIAA0587 KIAA0900 KIAA1168 MAPK1 MAPK3 NAP1 NCK NCK1 NCKAP1 NCKAP1L NCKIPSD PIR121 PRKM1 PRKM2 PRKM3 PTK2 RAC1 SCAR1 SCAR3 SOP2L SPIN90 SSH3BP1 TC25 WAS WASF1 WASF2 WASF3 WASL WASPIP WAVE1 WAVE2 WAVE3 WICH WIP WIPF1 WIPF2 WIPF3 WIRE
RNA Polymerase II Transcription Termination	ATP-dependent RNA helicase DDX39A Chromatin target of PRMT1 protein Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 2 Cleavage and polyadenylation specificity factor subunit 3 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage and polyadenylation specificity factor subunit 7 Cleavage stimulation factor subunit 1 Cleavage stimulation factor subunit 2 tau variant Cleavage stimulation factor subunit 2 Cleavage stimulation factor subunit 3 Eukaryotic initiation factor 4A-III Histone RNA hairpin-binding protein Leucine zipper protein 4 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Poly(A) polymerase alpha Polyadenylate-binding protein 2 Polymerase delta-interacting protein 3 Polyribonucleotide 5'-hydroxyl-kinase Clp1 Pre-mRNA 3'-end-processing factor FIP1 Pre-mRNA cleavage complex 2 protein Pcf11 Pre-mRNA-processing factor 17 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 Pre-mRNA-splicing factor SLU7 Protein CASC3 Protein mago nashi homolog 2 Protein mago nashi homolog RNA-binding protein 8A RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 3B SAP domain-containing ribonucleoprotein Serine/arginine repetitive matrix protein 1 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 9 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated proteins B and B' Spliceosome RNA helicase DDX39B Splicing factor U2AF 26 kDa subunit Splicing factor U2AF 35 kDa subunit Splicing factor U2AF 65 kDa subunit Symplekin THO complex subunit 1 THO complex subunit 2 THO complex subunit 3 THO complex subunit 4 THO complex subunit 5 THO complex subunit 6 THO complex subunit 7 U7 snRNA-associated Sm-like protein LSm10 U7 snRNA-associated Sm-like protein LSm11 UAP56-interacting factor Zinc finger CCCH domain-containing protein 11A Zinc finger protein 473 pre-mRNA 3' end processing protein WDR33	O00148 O15234 O43809 O60508 O75152 O94913 O95391 O95639 P14678 P26368 P33240 P38919 P51003 P52298 P61326 P62304 P62306 P62308 P62318 P82979 P83369 P84103 Q01081 Q01130 Q05048 Q05519 Q07955 Q08170 Q09161 Q10570 Q12996 Q13242 Q13243 Q13247 Q13769 Q13838 Q14493 Q15287 Q16629 Q6I9Y2 Q6UN15 Q86U42 Q86V81 Q86W42 Q8IYB3 Q8N684 Q8NI27 Q8WTR7 Q8WU68 Q92620 Q92797 Q92989 Q969L4 Q96A72 Q96FV9 Q96J01 Q96QD9 Q9BY77 Q9BZI7 Q9C0J8 Q9H0L4 Q9P127 Q9P2I0 Q9UKF6 Q9Y3Y2 Q9Y5S9	ALY ALYREF ASF BAT1 BEF C1orf77 C22orf19 CASC3 CBP20 CBP80 CDC40 CFIM25 CHTOP CLP1 COD CPSF1 CPSF100 CPSF160 CPSF2 CPSF25 CPSF3 CPSF30 CPSF4 CPSF5 CPSF7 CPSF73 CSTF1 CSTF2 CSTF2T CSTF3 CXorf3 DDX38 DDX39 DDX39A DDX39B DDX48 DHX38 EHB3 EIF4A3 FIP1 FIP1L1 FOP FYTTD1 HBP HCC1 HEAB HPR1 HRS KIAA0111 KIAA0224 KIAA0663 KIAA0689 KIAA0824 KIAA0983 KIAA1141 KIAA1367 KIAA1649 LDC2 LSM10 LSM11 LUZP4 MAGOH MAGOH2 MAGOHA MAGOHB MLN51 NAR NCBP NCBP1 NCBP2 NEB1 NIF3L1BP1 NUDT21 PAB2 PABP2 PABPN1 PAP PAPOLA PBSCF PBSCG PCF11 PDIP46 POLDIP3 PRP16 PRP17 PRPF17 RBM8 RBM8A RENT3B RHE RNPS1 SARNP SF2 SF2P33 SFRS1 SFRS11 SFRS2 SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SLBP SLU7 SNRPB SNRPB1 SNRPD3 SNRPE SNRPF SNRPG SPK SRM160 SRP20 SRP30C SRP40 SRP55 SRP75 SRRM1 SRSF1 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF9 SYMPK THOC1 THOC2 THOC3 THOC4 THOC5 THOC6 THOC7 U2AF1 U2AF1-RS3 U2AF1L3 U2AF1L4 U2AF2 U2AF35 U2AF65 U2AFBP UAP56 UIF UPF3B UPF3X WDC146 WDR33 WDR58 ZC3H11A ZC3HDC11A ZFP100 ZNF473
FGFR3b ligand binding and activation	Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 9	O76093 P05230 P31371 Q9NP95	FGF1 FGF18 FGF20 FGF9 FGFA
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	Apoptosis regulator BAX Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like BH3-interacting domain death agonist Bcl-2-binding component 3, isoforms 1/2 CREB-binding protein Cellular tumor antigen p53 Ferroptosis suppressor protein 1 Metalloreductase STEAP3 PRELI domain containing protein 3A PRELI domain-containing protein 1, mitochondrial Phorbol-12-myristate-13-acetate-induced protein 1 Serine-protein kinase ATM TP53-regulated inhibitor of apoptosis 1 Tumor protein 63 Tumor protein p53-inducible nuclear protein 1 Tumor protein p73 Zinc finger protein 420 p53-regulated apoptosis-inducing protein 1	O15350 O43715 O60238 P04637 P55957 Q07812 Q13315 Q13625 Q13794 Q658P3 Q8TAQ5 Q92793 Q96A56 Q96KQ4 Q96N28 Q9BRQ8 Q9BXH1 Q9H3D4 Q9HCN2 Q9Y255	15E1.1 AIFM2 AMID ASPP1 ASPP2 ATM BAX BBC3 BBP BCL2L4 BID BNIP3A BNIP3H BNIP3L C18orf43 CBP CREBBP KET KIAA0771 NIX NOXA P53 P53DINP1 P63 P73 P73H P73L PMAIP1 PPP1R13B PRELI PRELID1 PRELID3A PRG3 PUMA SIP SLMO1 STEAP3 TP53 TP53AIP1 TP53BP2 TP53INP1 TP63 TP73 TP73L TRIAP1 TSAP6 ZNF420
Transcriptional Regulation by MECP2	Guanidinoacetate N-methyltransferase Helicase MOV-10 Interleukin-1 receptor-associated kinase 1 Microprocessor complex subunit DGCR8 Myelin-associated oligodendrocyte basic protein Parvalbumin alpha Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Serine/threonine-protein kinase Sgk1 Transcription factor SOX-2 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	O00141 P20472 P48431 P51617 P60484 Q13875 Q14353 Q8NDV7 Q8WYQ5 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 C22orf12 CAGH26 DGCR8 DGCRK6 EIF2C1 EIF2C2 EIF2C3 EIF2C4 GAMT IRAK IRAK1 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 MMAC1 MOBP MOV10 PTEN PVALB SGK SGK1 SOX2 TEP1 TNRC6 TNRC6A TNRC6B TNRC6C
SARS-CoV-2 modulates autophagy	Elongation factor Tu, mitochondrial Membrane protein Microtubule-associated proteins 1A/1B light chain 3B ORF3a protein ORF7a protein UV radiation resistance-associated gene protein Vacuolar protein sorting-associated protein 11 homolog Vacuolar protein sorting-associated protein 16 homolog Vacuolar protein sorting-associated protein 18 homolog Vacuolar protein sorting-associated protein 33A Vacuolar protein sorting-associated protein 33B Vacuolar protein sorting-associated protein 41 homolog Vacuolar protein sorting-associated protein 45 Vam6/Vps39-like protein	P0DTC3 P0DTC5 P0DTC7 P49411 P49754 Q96AX1 Q96JC1 Q9GZQ8 Q9H267 Q9H269 Q9H270 Q9NRW7 Q9P253 Q9P2Y5	3a 7a KIAA0770 KIAA1475 M MAP1ALC3 MAP1LC3B RNF108 TLP TUFM UVRAG VAM6 VPS11 VPS16 VPS18 VPS33A VPS33B VPS39 VPS41 VPS45 VPS45A VPS45B
Lewis blood group biosynthesis	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 Alpha-(1,3)-fucosyltransferase 10 Alpha-(1,3)-fucosyltransferase 11 Alpha-(1,3)-fucosyltransferase 4 Alpha-(1,3)-fucosyltransferase 7 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Beta-1,3-galactosyltransferase 1 Beta-1,3-galactosyltransferase 2 Beta-1,3-galactosyltransferase 4 Beta-1,3-galactosyltransferase 5 Beta-1,4 N-acetylgalactosaminyltransferase 2 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Galactoside alpha-(1,2)-fucosyltransferase 2 Type 2 lactosamine alpha-2,3-sialyltransferase	O43825 O96024 P21217 P22083 P51993 Q10981 Q11128 Q11130 Q11203 Q11206 Q495W5 Q6P4F1 Q8NHY0 Q969X2 Q9Y231 Q9Y274 Q9Y2C3 Q9Y5Z6	B3GALT1 B3GALT2 B3GALT4 B3GALT5 B4GALNT2 CGS23 ELFT FCT3A FT3B FUT10 FUT11 FUT2 FUT3 FUT4 FUT5 FUT6 FUT7 FUT9 GALGT2 GALT4 LE NANTA3 SEC2 SIAT10 SIAT4C SIAT6 SIAT7F ST3GAL3 ST3GAL4 ST3GAL6 ST6GALNAC6 STZ	G39211DH G81971FM G83633HB G90387AM G98173LG
Cellular response to hypoxia	Endothelial PAS domain-containing protein 1 Hypoxia-inducible factor 1-alpha inhibitor Hypoxia-inducible factor 1-alpha	Q16665 Q99814 Q9NWT6	BHLHE73 BHLHE78 EPAS1 FIH1 HIF1A HIF1AN HIF2A MOP1 MOP2 PASD2 PASD8
CD28 dependent Vav1 pathway	Cell division control protein 42 homolog Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck	O75914 P06239 P06241 P10747 P15498 P33681 P42081 P60953 P63000 Q13153 Q13177	CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 CDC42 FYN LAB7 LCK OPHN3 PAK1 PAK2 PAK3 RAC1 TC25 VAV VAV1
Budding	Hemagglutinin Matrix protein 1 Matrix protein 2 Neuraminidase Nuclear export protein Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 RNA-directed RNA polymerase catalytic subunit	P03428 P03431 P03433 P03452 P03466 P03468 P03485 P03508 P06821	HA M NA NP NS PA PB1 PB2
Defective SLC7A7 causes lysinuric protein intolerance (LPI)	Amino acid transporter heavy chain SLC3A2 Y+L amino acid transporter 1	P08195 Q9UM01	MDU1 SLC3A2 SLC7A7
Passive transport by Aquaporins	Aquaporin-10 Aquaporin-11 Aquaporin-12A Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Aquaporin-5 Aquaporin-6 Aquaporin-7 Aquaporin-8 Aquaporin-9 Lens fiber major intrinsic protein	O14520 O43315 O94778 P29972 P30301 P41181 P55064 P55087 Q13520 Q8IXF9 Q8NBQ7 Q92482 Q96PS8	AQP0 AQP1 AQP10 AQP11 AQP12 AQP12A AQP2 AQP2L AQP3 AQP4 AQP5 AQP6 AQP7 AQP7L AQP8 AQP9 AQPX1 AQPX2 CHIP28 MIP SSC1
Regulation of pyruvate dehydrogenase (PDH) complex	Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Maleylacetoacetate isomerase NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial Pyruvate dehydrogenase protein X component, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial	O00330 O43708 P08559 P09622 P10515 P11177 P29803 Q15118 Q15119 Q15120 Q16654 Q8NCN5 Q9P0J1 Q9P2J9 Q9Y6E7	DLAT DLD DLTA GCSL GSTZ1 KIAA1348 KIAA1990 LAD MAAI PDHA1 PDHA2 PDHAL PDHB PDHK1 PDHK2 PDHK3 PDHK4 PDHX PDK1 PDK2 PDK3 PDK4 PDP PDP1 PDP2 PDPR PDX1 PHE1A PHE1B PHE3 PPM2C SIR2L4 SIRT4
Phase 3 - rapid repolarisation	A-kinase anchor protein 9 Potassium voltage-gated channel subfamily A member 5 Potassium voltage-gated channel subfamily E member 1 Potassium voltage-gated channel subfamily E member 2 Potassium voltage-gated channel subfamily E member 3 Potassium voltage-gated channel subfamily E member 4 Potassium voltage-gated channel subfamily E regulatory beta subunit 5 Potassium voltage-gated channel subfamily KQT member 1 Voltage-gated inwardly rectifying potassium channel KCNH2	P15382 P22460 P51787 Q12809 Q8WWG9 Q99996 Q9UJ90 Q9Y6H6 Q9Y6J6	AKAP350 AKAP450 AKAP9 AMMECR2 ERG ERG1 HERG KCNA5 KCNA8 KCNA9 KCNE1 KCNE1L KCNE2 KCNE3 KCNE4 KCNE5 KCNH2 KCNQ1 KIAA0803 KVLQT1
SUMOylation of DNA damage response and repair proteins	Aladin Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Centrin-2 Chromobox protein homolog 2 Chromobox protein homolog 8 Cohesin subunit SA-1 Cohesin subunit SA-2 DNA repair protein RAD52 homolog DNA repair protein XRCC4 DNA repair protein complementing XP-C cells Double-strand-break repair protein rad21 homolog E3 SUMO-protein ligase CBX4 E3 SUMO-protein ligase NSE2 E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS4 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 E3 ubiquitin-protein ligase RNF168 EP300-interacting inhibitor of differentiation 3 G/T mismatch-specific thymine DNA glycosylase Histone deacetylase 7 Mediator of DNA damage checkpoint protein 1 Non-structural maintenance of chromosomes element 1 homolog Non-structural maintenance of chromosomes element 3 homolog Non-structural maintenance of chromosomes element 4 homolog A Nuclear autoantigen Sp-100 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Poly [ADP-ribose] polymerase 1 Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 Protein PML Protein SEC13 homolog RecQ-like DNA helicase BLM Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Structural maintenance of chromosomes protein 5 Structural maintenance of chromosomes protein 6 Tumor suppressor ARF mRNA export factor RAE1	A8CG34 O00257 O15504 O60216 O75694 O75925 O95714 P09874 P12270 P23497 P27694 P29590 P35226 P35227 P35658 P37198 P38398 P41208 P43351 P49790 P49792 P54132 P55735 P55854 P57740 P61956 P63165 P63279 P78364 P78406 Q01831 Q06587 Q12769 Q13426 Q13569 Q14191 Q14676 Q14683 Q14781 Q5SRE5 Q7Z3B4 Q8IXK0 Q8IY18 Q8IYW5 Q8N140 Q8N1F7 Q8N2W9 Q8N3U4 Q8N726 Q8NDX5 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUI4 Q8WUM0 Q8WV22 Q8WVM7 Q92621 Q96HA1 Q96MF7 Q96MG7 Q96SB8 Q99496 Q99567 Q9BTX1 Q9BW27 Q9HC52 Q9NRG9 Q9NXX6 Q9UKX7 Q9UQE7	AAAS ADPRT ADRACALA BAM BAP1 BLM BMH BMI1 BRCA1 C10orf86 C7orf14 C8orf36 CAIN CALT CAN CBX2 CBX4 CBX8 CDKN2 CDKN2A CEN2 CETN2 CG1 CSPG6 D3S1231E DDXBP1 DING DXS423E EDR1 EDR2 EDR3 EID3 HCA4 HDAC7 HDAC7A HERC2 HIPI3 HR21 KIAA0023 KIAA0078 KIAA0095 KIAA0169 KIAA0170 KIAA0178 KIAA0197 KIAA0225 KIAA0594 KIAA0618 KIAA0791 KIAA0906 MAGEG1 MDC1 MEL18 MLM MMS21 MP44 MRNP41 MYL NDC1 NDNL2 NFBD1 NPAP60L NSMCE1 NSMCE2 NSMCE3 NSMCE4A NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 NXP1 PARP1 PC3 PCGF2 PCGF4 PCNT1 PH1 PH2 PH3 PHC1 PHC2 PHC3 PIAS1 PIAS4 PIASG PML POM121 POM121A POM121C PP8675 PPOL RAD21 RAD52 RAE1 RANBP2 RC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 RING1 RING1A RING1B RNF1 RNF110 RNF168 RNF2 RNF51 RNF53 RNF71 RPA1 RPA70 SA1 SA2 SB1.8 SCC1 SCC3 SEC13 SEC13A SEC13L1 SEC13R SMC1 SMC1A SMC1L1 SMC3 SMC3L1 SMC5 SMC5L1 SMC6 SMC6L1 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SP100 STAG1 STAG2 SUMO1 SUMO2 SUMO3 TDG TMEM48 TPR TRIM19 UBC9 UBCE9 UBE2I UBL1 WRN XPC XPCC XRCC4 ZNF144
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	CREB-binding protein Core-binding factor subunit beta Galectin-3 Granulocyte-macrophage colony-stimulating factor Protein kinase C beta type Runt-related transcription factor 1	P04141 P05771 P17931 Q01196 Q13951 Q92793	AML1 CBFA2 CBFB CBP CREBBP CSF2 GMCSF LGALS3 MAC2 PKCB PRKCB PRKCB1 RUNX1
FCERI mediated MAPK activation	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Dual specificity mitogen-activated protein kinase kinase 4 Dual specificity mitogen-activated protein kinase kinase 7 GRB2-related adapter protein 2 GTPase HRas GTPase NRas Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 IGHV7-81 protein Immunoglobulin heavy constant epsilon Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Lymphocyte cytosolic protein 2 Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Mitogen-activated protein kinase kinase kinase 1 Protein c-Fos Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Son of sevenless homolog 1 Transcription factor Jun Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O14733 O75791 P01100 P01111 P01112 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01854 P04211 P04430 P04432 P04433 P05412 P06310 P06312 P06315 P06331 P07948 P0CF74 P0CG04 P0DOY2 P0DOY3 P15498 P16885 P19174 P23083 P27361 P28482 P43405 P45983 P45984 P45985 P52735 P53779 P63000 P80748 Q07889 Q13094 Q13153 Q13177 Q13233 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q9UKW4	ERK1 ERK2 FOS G0S7 GADS GRAP2 GRB2L GRID HRAS HRAS1 IGHE IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 JNK1 JNK2 JNK3 JNK3A JNKK1 JNKK2 JTK8 JUN LCP2 LYN MAP2K4 MAP2K7 MAP3K1 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MAPKKK1 MEK4 MEK7 MEKK MEKK1 MKK4 MKK7 NRAS PAK1 PAK2 PLC1 PLCG1 PLCG2 PRKM1 PRKM10 PRKM2 PRKM3 PRKM8 PRKM9 PRKMK4 PRKMK7 RAC1 SAPK1 SAPK1A SAPK1B SAPK1C SEK1 SERK1 SKK1 SKK4 SOS1 SYK TC25 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VAV VAV1 VAV2 VAV3
Defective SLC17A5 causes Salla disease (SD) and ISSD	Sialin	Q9NRA2	SLC17A5
Defective SLC22A12 causes renal hypouricemia 1 (RHUC1)	Solute carrier family 22 member 12	Q96S37	OATL4 SLC22A12 URAT1
OAS antiviral response	2',5'-phosphodiesterase 12 2'-5'-oligoadenylate synthase 1 2'-5'-oligoadenylate synthase 2 2'-5'-oligoadenylate synthase 3 2'-5'-oligoadenylate synthase-like protein 2-5A-dependent ribonuclease ATP-binding cassette sub-family E member 1 Antiviral innate immune response receptor RIG-I Filamin-A Protein VP3	B1NKT1 O95786 P00973 P21333 P29728 P61221 Q05823 Q15646 Q6L8Q7 Q9Y6K5	ABCE1 DDX58 FLN FLN1 FLNA OAS1 OAS2 OAS3 OASL OIAS PDE12 RIGI RLI RNASEL RNASEL1 RNASELI RNS4 RNS4I TRIP14
InlA-mediated entry of Listeria monocytogenes into host cells	Cadherin-1 Catenin beta-1 Catenin delta-1 E3 ubiquitin-protein ligase Hakai Internalin A Polyubiquitin-B Polyubiquitin-C Proto-oncogene tyrosine-protein kinase Src Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O60716 P0CG47 P0CG48 P0DJM0 P12830 P12931 P35222 P62979 P62987 Q75N03	CBLL1 CDH1 CDHE CTNNB CTNNB1 CTNND1 HAKAI KIAA0384 RNF188 RPS27A SRC SRC1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UVO inlA

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