GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (10109) Glycans (5831) Glycoproteins (15837) Lectins (297) Pathways (2074)

Displaying entries **551 - 575** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol
Inhibition of Signaling by Overexpressed EGFR	Amphiregulin Epidermal growth factor receptor Epigen Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha	O14944 P00533 P01133 P01135 P15514 P35070 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 SDGF TGFA
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O60825 P16118 P17612 P22612 P22694 P30153 P30154 P62714 P67775 Q14738 Q16875 Q16877	F6PK PFKFB1 PFKFB2 PFKFB3 PFKFB4 PFRX PKACA PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PRKACA PRKACB PRKACG
Negative regulation of MET activity	E3 ubiquitin-protein ligase CBL Endophilin-A1 Endophilin-A2 Endophilin-A3 Epidermal growth factor receptor substrate 15 Hepatocyte growth factor receptor Hepatocyte growth factor-regulated tyrosine kinase substrate Hepatocyte growth factor Leucine-rich repeats and immunoglobulin-like domains protein 1 Polyubiquitin-B Polyubiquitin-C Receptor-type tyrosine-protein phosphatase eta SH3 domain-containing kinase-binding protein 1 Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 2 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14964 O75886 P08581 P0CG47 P0CG48 P14210 P17706 P18031 P22681 P40818 P42566 P62979 P62987 Q12913 Q92783 Q96B97 Q96JA1 Q99961 Q99962 Q99963	AF1P CBL CBL2 CIN85 CNSA1 CNSA2 CNSA3 DEP1 EPS15 HBP HGF HGS HPTA HRS KIAA0055 LIG1 LRIG1 MET PTP1B PTPN1 PTPN2 PTPRJ PTPT RNF55 RPS27A SH3D2A SH3D2B SH3D2C SH3GL1 SH3GL2 SH3GL3 SH3KBP1 STAM STAM1 STAM2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBPY USP8
Interferon gamma signaling	2'-5'-oligoadenylate synthase 1 2'-5'-oligoadenylate synthase 2 2'-5'-oligoadenylate synthase 3 2'-5'-oligoadenylate synthase-like protein Beta-2-microglobulin CD44 antigen Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma E3 ubiquitin-protein ligase Midline-1 E3 ubiquitin-protein ligase TRIM17 E3 ubiquitin-protein ligase TRIM21 E3 ubiquitin-protein ligase TRIM22 E3 ubiquitin-protein ligase TRIM31 E3 ubiquitin-protein ligase TRIM34 E3 ubiquitin-protein ligase TRIM35 E3 ubiquitin-protein ligase TRIM38 E3 ubiquitin-protein ligase TRIM45 E3 ubiquitin-protein ligase TRIM48 E3 ubiquitin-protein ligase TRIM62 E3 ubiquitin-protein ligase TRIM68 E3 ubiquitin-protein ligase TRIM8 E3 ubiquitin/ISG15 ligase TRIM25 Gamma-interferon-inducible lysosomal thiol reductase Guanylate-binding protein 1 Guanylate-binding protein 2 Guanylate-binding protein 3 Guanylate-binding protein 4 Guanylate-binding protein 5 Guanylate-binding protein 6 Guanylate-binding protein 7 HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain High affinity immunoglobulin gamma Fc receptor I Intercellular adhesion molecule 1 Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Interferon regulatory factor 1 Interferon regulatory factor 2 Interferon regulatory factor 3 Interferon regulatory factor 4 Interferon regulatory factor 5 Interferon regulatory factor 6 Interferon regulatory factor 7 Interferon regulatory factor 8 Interferon regulatory factor 9 MHC class II transactivator Metallothionein-2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 7 Neural cell adhesion molecule 1 Nuclear autoantigen Sp-100 Platelet-activating factor receptor Protein PML Protein kinase C delta type Putative HLA class I histocompatibility antigen, alpha chain H Putative high affinity immunoglobulin gamma Fc receptor IB Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tripartite motif-containing protein 10 Tripartite motif-containing protein 14 Tripartite motif-containing protein 26 Tripartite motif-containing protein 29 Tripartite motif-containing protein 2 Tripartite motif-containing protein 3 Tripartite motif-containing protein 46 Tripartite motif-containing protein 5 Tripartite motif-containing protein 6 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 6 Vascular cell adhesion protein 1 Y-box-binding protein 1	O00635 O14543 O14896 O15105 O15344 O15524 O60674 O75382 P00973 P01579 P01889 P01893 P01903 P01906 P01909 P01911 P01920 P02795 P04439 P04440 P05362 P05538 P10321 P10914 P12314 P13284 P13591 P13747 P13762 P14316 P15260 P16070 P17693 P19320 P19474 P20036 P23458 P23497 P25105 P27361 P28482 P29350 P29590 P29728 P30511 P32455 P32456 P33076 P38484 P61769 P67809 P79483 Q00978 Q02556 Q05655 Q12899 Q13554 Q13555 Q13557 Q13568 Q14134 Q14142 Q14258 Q14653 Q15306 Q15646 Q30154 Q6AZZ1 Q6ZN66 Q7Z4K8 Q8IWZ4 Q8IYM9 Q8N8V2 Q92637 Q92985 Q96PP8 Q96PP9 Q9BVG3 Q9BYJ4 Q9BZR9 Q9BZY9 Q9C030 Q9C035 Q9C040 Q9H0R5 Q9H8W5 Q9UDY6 Q9UPQ4 Q9UQM7 Q9Y577 Q9Y6K5	ATDC B2M BERP C6orf13 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CD44 CES1 CIITA CIS3 EFP ERK1 ERK2 FCG1 FCGR1 FCGR1A FCGR1B FCGR1BP FXY GBP1 GBP2 GBP3 GBP4 GBP4L GBP5 GBP6 GBP7 GC109 GERP GILT HCP HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH HLASB HLS5 ICAM1 ICSBP1 IFI30 IFNG IFNGR1 IFNGR2 IFNGT1 IFP1 IGFR1 IGFRB IP30 IRF1 IRF2 IRF3 IRF4 IRF5 IRF6 IRF7 IRF8 IRF9 ISGF3G JAK1 JAK1A JAK1B JAK2 KIAA0129 KIAA0517 KIAA0968 KIAA1098 LHR MADH7 MADH8 MAPK1 MAPK3 MDU2 MDU3 MHC2TA MIC4 MID1 MT2 MT2A MUM1 MYL NCAM NCAM1 NSEP1 OAS1 OAS2 OAS3 OASL OIAS PAFR PKCD PML PP8675 PRKCD PRKM1 PRKM2 PRKM3 PTAFR PTP1C PTPN6 RBCC RFB30 RNF RNF101 RNF137 RNF147 RNF15 RNF16 RNF21 RNF22 RNF27 RNF59 RNF71 RNF81 RNF86 RNF88 RNF89 RNF9 RNF94 RNF95 RNF97 RNF99 RO52 RORET SMAD7 SOCS1 SOCS3 SP100 SS56 SSA1 SSI1 SSI3 STAF50 TERF TIP3 TRIFIC TRIM10 TRIM14 TRIM17 TRIM18 TRIM19 TRIM2 TRIM21 TRIM22 TRIM25 TRIM26 TRIM29 TRIM3 TRIM31 TRIM34 TRIM35 TRIM38 TRIM45 TRIM46 TRIM48 TRIM5 TRIM6 TRIM62 TRIM68 TRIM8 TRIP14 VCAM1 XPRF YB1 YBX1 ZNF147 ZNF173
Ligand-independent caspase activation via DCC	Caspase-3 Caspase-9 DCC-interacting protein 13-alpha Death-associated protein kinase 1 Death-associated protein kinase 2 Death-associated protein kinase 3 Melanoma-associated antigen D1 Netrin receptor DCC Netrin receptor UNC5A Netrin receptor UNC5B	O43293 P42574 P43146 P53355 P55211 Q6ZN44 Q8IZJ1 Q9UIK4 Q9UKG1 Q9Y5V3	APPL APPL1 CASP3 CASP9 CPP32 DAPK DAPK1 DAPK2 DAPK3 DCC DIP13A IGDCC1 KIAA1428 KIAA1976 MAGED1 MCH6 NRAGE P53RDL1 UNC5A UNC5B UNC5H1 UNC5H2 ZIPK
Axonal growth stimulation	Beta-nerve growth factor Rho GDP-dissociation inhibitor 1 Transforming protein RhoA Tumor necrosis factor receptor superfamily member 16	P01138 P08138 P52565 P61586	ARH12 ARHA ARHGDIA GDIA1 NGF NGFB NGFR RHO12 RHOA TNFRSF16
Biotin transport and metabolism	Acetyl-CoA carboxylase 1 Acetyl-CoA carboxylase 2 Biotin--protein ligase Biotinidase Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial PDZ domain-containing protein 11 Propionyl-CoA carboxylase alpha chain, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial Pyruvate carboxylase, mitochondrial Sodium-dependent multivitamin transporter	O00763 P05165 P05166 P11498 P43251 P50747 Q13085 Q5EBL8 Q96RQ3 Q9HCC0 Q9Y289	ACAC ACACA ACACB ACC1 ACC2 ACCA ACCB AIPP1 BTD HLCS MCCA MCCB MCCC1 MCCC2 PC PCCA PCCB PDZD11 PDZK11 PISP SLC5A6 SMVT
Acyl chain remodeling of DAG and TAG	1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 Acyl-CoA wax alcohol acyltransferase 2 Diacylglycerol O-acyltransferase 1 Diacylglycerol O-acyltransferase 2-like protein 6 Diacylglycerol O-acyltransferase 2 Monoglyceride lipase Patatin-like phospholipase domain-containing protein 2	O75907 Q6E213 Q6ZPD8 Q96AD5 Q96PD7 Q99685 Q9NST1	ADPN AGRP1 ATGL AWAT2 C22orf20 DC3 DC4 DGAT DGAT1 DGAT2 DGAT2L4 DGAT2L6 MFAT MGLL PNPLA2 PNPLA3 WS
FGFRL1 modulation of FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 18 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor receptor-like 1 Sprouty-related, EVH1 domain-containing protein 1 Sprouty-related, EVH1 domain-containing protein 2	O15520 O76093 P08620 P09038 P11487 Q7Z698 Q7Z699 Q8N441 Q9GZV9 Q9HCT0	FGF10 FGF18 FGF2 FGF22 FGF23 FGF3 FGF4 FGFB FGFR5 FGFRL1 FHFR HST HSTF1 HYPF INT2 KS3 SPRED1 SPRED2
Cytochrome P450 - arranged by substrate type	NADPH--cytochrome P450 reductase	P16435	CYPOR POR
Intraflagellar transport	Clusterin-associated protein 1 Cytoplasmic dynein 2 heavy chain 1 Cytoplasmic dynein 2 intermediate chain 1 Cytoplasmic dynein 2 intermediate chain 2 Cytoplasmic dynein 2 light intermediate chain 1 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Dynein light chain Tctex-type 5 Dynein light chain Tctex-type protein 2 Dynein light chain Tctex-type protein 2B Dynein light chain roadblock-type 1 Dynein light chain roadblock-type 2 Intraflagellar transport protein 122 homolog Intraflagellar transport protein 140 homolog Intraflagellar transport protein 172 homolog Intraflagellar transport protein 20 homolog Intraflagellar transport protein 22 homolog Intraflagellar transport protein 25 homolog Intraflagellar transport protein 27 homolog Intraflagellar transport protein 43 homolog Intraflagellar transport protein 46 homolog Intraflagellar transport protein 52 homolog Intraflagellar transport protein 56 Intraflagellar transport protein 57 homolog Intraflagellar transport protein 70A Intraflagellar transport protein 70B Intraflagellar transport protein 74 homolog Intraflagellar transport protein 80 homolog Intraflagellar transport protein 81 homolog Intraflagellar transport protein 88 homolog Kinesin-associated protein 3 Kinesin-like protein KIF17 Kinesin-like protein KIF3A Kinesin-like protein KIF3B Kinesin-like protein KIF3C TRAF3-interacting protein 1 Tetratricopeptide repeat protein 21B Thyroid receptor-interacting protein 11 Transportin-1 WD repeat-containing protein 19 WD repeat-containing protein 35	A0AVF1 O14782 O15066 P63167 Q13099 Q15643 Q7Z4L5 Q86WT1 Q8IY31 Q8IZS6 Q8N4P2 Q8N7M0 Q8NCM8 Q8NEZ3 Q8TCX1 Q8TDR0 Q8TF09 Q8WVS4 Q8WW35 Q8WYA0 Q92845 Q92973 Q96AJ1 Q96EX3 Q96FJ2 Q96FT9 Q96LB3 Q96RY7 Q9BW83 Q9H7X7 Q9HBG6 Q9NP97 Q9NQC8 Q9NWB7 Q9P2E2 Q9P2H3 Q9P2L0 Q9UG01 Q9Y366 Q9Y496 Q9Y547	BITH C11orf2 C11orf60 C14orf179 C1orf41 C20orf9 CCDC2 CDV1 CEV14 CLUAP1 CMG1 D2LIC DERP8 DHC1B DHC2 DLC1 DLC2 DNCH2 DNCL1 DNCL2A DNCL2B DNCLC1 DNLC2A DNLC2B DYH1B DYNC2H1 DYNC2I1 DYNC2I2 DYNC2LI1 DYNLL1 DYNLL2 DYNLRB1 DYNLRB2 DYNLT2 DYNLT2B DYNLT5 ESRRBL1 HDLC1 HIPPI HSPB11 IFT121 IFT122 IFT139 IFT140 IFT144 IFT172 IFT20 IFT22 IFT25 IFT27 IFT43 IFT46 IFT52 IFT54 IFT56 IFT57 IFT70A IFT70B IFT74 IFT80 IFT81 IFT88 KIAA0359 KIAA0590 KIAA0643 KIAA1179 KIAA1336 KIAA1374 KIAA1405 KIAA1638 KIAA1992 KIAA1997 KIF17 KIF3 KIF3A KIF3AP KIF3B KIF3C KIF3X KIFAP3 KPNB2 LIC3 MIP1 MIPT3 NGD5 RABL4 RABL5 RAYL ROBLD1 ROBLD2 SMAP SPG TCTE3 TCTEX1D1 TCTEX1D2 TCTEX1D3 TG737 TNPO1 TRAF3IP1 TRIP11 TRN TTC10 TTC21B TTC26 TTC30A TTC30B WDR10 WDR140 WDR19 WDR34 WDR35 WDR56 WDR60 WDTC2
CLEC7A (Dectin-1) induces NFAT activation	Calcineurin subunit B type 1 Calmodulin-1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Nuclear factor of activated T-cells, cytoplasmic 1 Nuclear factor of activated T-cells, cytoplasmic 2 Nuclear factor of activated T-cells, cytoplasmic 3 Protein phosphatase 3 catalytic subunit alpha S-adenosylhomocysteine hydrolase-like protein 1 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform	O43865 O95644 P0DP23 P16298 P63098 Q08209 Q12968 Q13469 Q14571 Q14573 Q14643	AHCYL1 CALM CALM1 CALNA CALNA2 CALNB CAM CAM1 CNA CNA2 CNB DCAL INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 NFAT1 NFAT2 NFAT4 NFATC NFATC1 NFATC2 NFATC3 NFATP PPP3CA PPP3CB PPP3R1 XPVKONA
FRS-mediated FGFR4 signaling	Beta-klotho Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43320 O43559 O76093 O95750 P01111 P01112 P05230 P08620 P09038 P10767 P22455 P31371 Q06124 Q07889 Q86Z14 Q8WU20 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1 TKF
Biosynthesis of DPAn-3 SPMs	Prostaglandin G/H synthase 2	P35354	COX2 PTGS2
Aflatoxin activation and detoxification	Aflatoxin B1 aldehyde reductase member 2 Aflatoxin B1 aldehyde reductase member 3 Aflatoxin B1 aldehyde reductase member 4 Aminoacylase-1 Cytochrome P450 1A2 Cytochrome P450 2A13 Cytochrome P450 3A4 Cytochrome P450 3A5 Dipeptidase 1 Dipeptidase 2 Glutathione S-transferase 3, mitochondrial Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Microsomal glutathione S-transferase 1 Microsomal glutathione S-transferase 2 N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) Putative glutathione hydrolase 3 proenzyme	A6NGU5 O14880 O43488 O95154 P05177 P08684 P10620 P16444 P19440 P20815 P36269 Q03154 Q16696 Q6P531 Q8NHP1 Q96HD9 Q99735 Q9H4A9 Q9UJ14	ACY1 ACY3 AFAR AFAR1 AFAR2 AFAR3 AKR7 AKR7A2 AKR7A3 AKR7A4 AKR7L ASPA2 CYP1A2 CYP2A13 CYP3A3 CYP3A4 CYP3A5 DPEP1 DPEP2 GGT GGT1 GGT3 GGT3P GGT5 GGT6 GGT7 GGTL3 GGTL5 GGTLA1 GST12 GST2 MDP MGST MGST1 MGST2 MGST3 RDP
CHL1 interactions	Ankyrin-1 Contactin-6 Heat shock cognate 71 kDa protein Integrin alpha-10 Integrin alpha-1 Integrin alpha-2 Integrin beta-1 Neural cell adhesion molecule L1-like protein Neuropilin-1	O00533 O14786 O75578 P05556 P11142 P16157 P17301 P56199 Q9UQ52	ANK ANK1 CALL CD49B CHL1 CNTN6 FNRB HSC70 HSP73 HSPA10 HSPA8 ITGA1 ITGA10 ITGA2 ITGB1 MDF2 MSK12 NRP NRP1 VEGF165R
Signaling by ALK	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 ALK and LTK ligand 1 ALK and LTK ligand 2 ALK tyrosine kinase receptor Fibroblast growth factor receptor substrate 2 Insulin receptor substrate 1 Midkine Myc proto-oncogene protein N-myc proto-oncogene protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Pleiotrophin Signal transducer and activator of transcription 3 Tyrosine-protein kinase JAK3 Tyrosine-protein phosphatase non-receptor type 6	O00459 P01106 P04198 P19174 P21246 P21741 P27986 P29350 P35568 P40763 P42336 P42338 P52333 Q6UX46 Q6UXT8 Q8WU20 Q9UM73	ALK ALKAL1 ALKAL2 APRF BHLHE37 BHLHE39 FAM150A FAM150B FRS2 GRB1 HBNF1 HCP IRS1 JAK3 MDK MK1 MYC MYCN NEGF1 NEGF2 NMYC PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLC1 PLCG1 PTN PTP1C PTPN6 STAT3
NOTCH2 Activation and Transmission of Signal to the Nucleus	Contactin-1 Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Midkine Neurogenic locus notch homolog protein 2 Nicastrin Notch homolog 2 N-terminal-like protein A Notch homolog 2 N-terminal-like protein B Notch homolog 2 N-terminal-like protein C Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Protein jagged-1 Protein jagged-2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00548 O14672 O76050 P0CG47 P0CG48 P0DPK3 P0DPK4 P21741 P49768 P49810 P62979 P62987 P78504 Q04721 Q12860 Q7Z3S9 Q86YT6 Q8WW43 Q92542 Q96AX9 Q96BI3 Q9NR61 Q9NZ42 Q9Y219	AD3 AD4 ADAM10 APH1A APH1B CNTN1 DIP1 DLL1 DLL4 JAG1 JAG2 JAGL1 KIAA0253 KIAA1323 KUZ MADM MDK MIB1 MIB2 MK1 N2N NCSTN NEGF2 NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH2 NOTCH2NL NOTCH2NLA NOTCH2NLB NOTCH2NLC PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF67 RPS27A SKD STM2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZZANK1 ZZANK2
Platelet Aggregation (Plug Formation)	Platelet glycoprotein IX Platelet glycoprotein Ib alpha chain Platelet glycoprotein Ib beta chain Platelet glycoprotein V Prothrombin Thrombopoietin receptor Thrombopoietin von Willebrand factor	P00734 P04275 P07359 P13224 P14770 P40197 P40225 P40238	F2 F8VWF GP1BA GP1BB GP5 GP9 MGDF MPL THPO TPOR VWF
Regulation of BACH1 activity	Cullin-1 E3 ubiquitin-protein ligase RBX1 F-box/LRR-repeat protein 17 Polyubiquitin-B Polyubiquitin-C S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Transcription factor MafK Transcription regulator protein BACH1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14867 O60675 P0CG47 P0CG48 P62877 P62979 P62987 P63208 Q13309 Q13616 Q9UF56	BACH1 CUL1 EMC19 FBL17 FBX13 FBXL1 FBXL17 FBXO13 MAFK OCP2 RBX1 RNF75 ROC1 RPS27A SKP1 SKP1A SKP2 TCEB1L UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
FCGR3A-mediated phagocytosis	Abl interactor 1 Abl interactor 2 Actin nucleation-promoting factor WAS Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Adapter molecule crk BAR/IMD domain-containing adapter protein 2 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 Dedicator of cytokinesis protein 1 Engulfment and cell motility protein 1 Engulfment and cell motility protein 2 Focal adhesion kinase 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 IGHV7-81 protein Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 2 Immunoglobulin heavy constant gamma 3 Immunoglobulin heavy constant gamma 4 Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Low affinity immunoglobulin gamma Fc region receptor III-A Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Myosin-2 Myosin-9 NCK-interacting protein with SH3 domain Nck-associated protein 1-like Nck-associated protein 1 Protein BRICK1 Proto-oncogene vav Putative GIPL galf transferase Ras-related C3 botulinum toxin substrate 1 SH2/SH3 adapter protein NCK1 T-cell surface glycoprotein CD3 gamma chain Tyrosine-protein kinase ABL1 Tyrosine-protein kinase BTK Tyrosine-protein kinase Fgr Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Yes UGa8H (Fragment) Unconventional myosin-IXb Unconventional myosin-Ic Unconventional myosin-Va Unconventional myosin-X V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment) WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 2 WAS/WASL-interacting protein family member 3	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 A6NGB9 O00159 O00401 O15143 O15144 O15145 O15511 O43516 P00519 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01857 P01859 P01860 P01861 P04211 P04430 P04432 P04433 P06241 P06310 P06312 P06315 P06331 P07947 P07948 P08631 P08637 P09693 P09769 P0CF74 P0CG04 P0DOY2 P0DOY3 P15498 P16333 P23083 P27361 P28482 P35579 P42768 P43405 P46108 P52735 P55160 P59998 P60709 P60953 P61158 P61160 P63000 P63261 P80748 Q05397 Q06187 Q13459 Q14185 Q4QD44 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q7L576 Q8IZP0 Q8TF74 Q8WUW1 Q92556 Q92558 Q92747 Q96F07 Q96JJ3 Q9HD67 Q9NYB9 Q9NZQ3 Q9UKW4 Q9UKX2 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y4I1 Q9Y6W5	ABI1 ABI2 ABL ABL1 ACTB ACTG ACTG1 ACTR2 ACTR3 AF3P21 AGMX1 ARC16 ARC20 ARC21 ARC34 ARC41 ARGBPIA ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ATK BAIAP2 BPK BRK1 BTK C3orf10 CD16A CD3G CDC42 CED12A CR16 CRK CYFIP1 CYFIP2 DOCK1 ELMO1 ELMO2 ERK1 ERK2 FAK FAK1 FCG3 FCGR3 FCGR3A FGR FYN HCK HEM1 HEM2 IGFR3 IGHG1 IGHG2 IGHG3 IGHG4 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 IMD2 JTK7 JTK8 KIAA0068 KIAA0269 KIAA0281 KIAA0587 KIAA0799 KIAA0900 KIAA1168 KIAA1834 LPG1G LPG1G2 LYN MAPK1 MAPK3 MYH12 MYH2 MYH9 MYHSA2 MYO10 MYO1C MYO5A MYO9B MYR5 NAP1 NCK NCK1 NCKAP1 NCKAP1L NCKIPSD PIR121 PRKM1 PRKM2 PRKM3 PTK2 RAC1 SCAR1 SCAR3 SOP2L SPIN90 SRC2 SSH3BP1 SYK T3G TC25 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VAV VAV1 VAV2 VAV3 WAS WASF1 WASF2 WASF3 WASL WASPIP WAVE1 WAVE2 WAVE3 WICH WIP WIPF1 WIPF2 WIPF3 WIRE YES YES1
Ethanol oxidation	Acetyl-coenzyme A synthetase 2-like, mitochondrial Acetyl-coenzyme A synthetase, cytoplasmic Alcohol dehydrogenase 1A Alcohol dehydrogenase 1C Alcohol dehydrogenase 6 Alcohol dehydrogenase class-3 Aldehyde dehydrogenase 1A1 Aldehyde dehydrogenase X, mitochondrial Aldehyde dehydrogenase, mitochondrial All-trans-retinol dehydrogenase [NAD(+)] ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH4 All-trans-retinol dehydrogenase [NAD(+)] ADH7	P00325 P00326 P00352 P05091 P07327 P08319 P11766 P28332 P30837 P40394 Q9NR19 Q9NUB1	ACAS2 ACAS2L ACSS1 ACSS2 ADH1 ADH1A ADH1B ADH1C ADH2 ADH3 ADH4 ADH5 ADH6 ADH7 ADHX ALDC ALDH1 ALDH1A1 ALDH1B1 ALDH2 ALDH5 ALDHX ALDM FDH KIAA1846 PUMB1
Nuclear events mediated by NFE2L2	5'-AMP-activated protein kinase catalytic subunit alpha-2 CREB-binding protein Histone acetyltransferase p300 Kelch-like ECH-associated protein 1 Nuclear factor erythroid 2-related factor 2 Sequestosome-1 Transcription factor MafG Transcription factor MafK Tumor suppressor ARF	O15525 O60675 P54646 Q09472 Q13501 Q14145 Q16236 Q8N726 Q92793	AMPK AMPK2 CBP CDKN2 CDKN2A CREBBP EP300 INRF2 KEAP1 KIAA0132 KLHL19 MAFG MAFK MLM NFE2L2 NRF2 ORCA OSIL P300 PRKAA2 SQSTM1
Defective F9 variant does not activate FX	Coagulation factor IX Coagulation factor VIII Coagulation factor X	P00451 P00740 P00742	F10 F8 F8C F9
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids	2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial Enoyl-CoA delta isomerase 1, mitochondrial Long-chain specific acyl-CoA dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P11310 P28330 P40939 P42126 P55084 Q16698	ACADL ACADM DCI DECR DECR1 ECI1 HADH HADHA HADHB SDR18C1

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