GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (10109) Glycans (5831) Glycoproteins (15837) Lectins (297) Pathways (2074)

Displaying entries **501 - 525** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	GlyTouCan ID
Defective GCK causes maturity-onset diabetes of the young 2 (MODY2)	Hexokinase-4	P35557	GCK	G58161NS
FGFR4 ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4	O43320 O76093 O95750 P05230 P08620 P09038 P10767 P22455 P31371 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 HST HST2 HSTF1 HSTF2 HYPF JTK2 KS3 TKF
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation	Homeobox protein NANOG POU domain, class 5, transcription factor 1 Transcription factor SOX-2	P48431 Q01860 Q9H9S0	NANOG OCT3 OCT4 OTF3 POU5F1 SOX2
Phenylalanine metabolism	Dihydropteridine reductase Isoaspartyl peptidase/L-asparaginase Kynurenine--oxoglutarate transaminase 1 L-amino-acid oxidase Phenylalanine-4-hydroxylase Pterin-4-alpha-carbinolamine dehydratase	P00439 P09417 P61457 Q16773 Q7L266 Q96RQ9	ALP ASRGL1 CCBL1 CRASH DCOH DHPR FIG1 IL4I1 KYAT1 PAH PCBD PCBD1 QDPR SDR33C1
TGF-beta receptor signaling activates SMADs	E3 ubiquitin-protein ligase CBL Furin Integrin alpha-8 Integrin alpha-V Integrin beta-1 Integrin beta-3 Integrin beta-5 Integrin beta-6 Integrin beta-8 Latent-transforming growth factor beta-binding protein 1 Latent-transforming growth factor beta-binding protein 2 Latent-transforming growth factor beta-binding protein 3 Latent-transforming growth factor beta-binding protein 4 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 NEDD8-conjugating enzyme Ubc12 NEDD8 Peptidyl-prolyl cis-trans isomerase FKBP1A TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta receptor type 3 Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta-3 proprotein	P01137 P05106 P05556 P06756 P09958 P10600 P18084 P18564 P22681 P26012 P36897 P37173 P53708 P61081 P61812 P62942 P84022 Q03167 Q13485 Q14766 Q14767 Q15796 Q15843 Q8N2S1 Q9NS15	ALK5 C14orf141 CBL CBL2 DPC4 FKBP1 FKBP12 FKBP1A FNRB FUR FURIN GP3A ITGA8 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP2 LTBP3 LTBP4 MADH2 MADH3 MADH4 MADR2 MDF2 MSK12 MSK8 NEDD8 PACE PCSK3 RNF55 SKR4 SMAD2 SMAD3 SMAD4 TGFB TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TGFBR3 UBC12 UBE2M VNRA VTNR
Maturation of nucleoprotein	Casein kinase I isoform alpha Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Nucleoprotein Protein arginine N-methyltransferase 1 Protein mono-ADP-ribosyltransferase PARP10 Protein mono-ADP-ribosyltransferase PARP14 Protein mono-ADP-ribosyltransferase PARP16 Protein mono-ADP-ribosyltransferase PARP4 Protein mono-ADP-ribosyltransferase PARP6 Protein mono-ADP-ribosyltransferase PARP8 Protein mono-ADP-ribosyltransferase PARP9 SRSF protein kinase 1 SRSF protein kinase 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1	P0DTC9 P48729 P49840 P49841 P63165 P63279 P78362 Q2NL67 Q460N5 Q53GL7 Q8IXQ6 Q8N3A8 Q8N5Y8 Q96SB4 Q99873 Q9UKK3	ADPRTL1 ARTD15 BAL BAL1 BAL2 C15orf30 CSNK1A1 GSK3A GSK3B HMT2 HRMT1L2 IR1B4 KIAA0177 KIAA1268 N PARP10 PARP14 PARP16 PARP4 PARP6 PARP8 PARP9 PARPL PRMT1 SMT3C SMT3H3 SRPK1 SRPK2 SUMO1 UBC9 UBCE9 UBE2I UBL1
Negative regulation of TCF-dependent signaling by DVL-interacting proteins	CXXC-type zinc finger protein 4 Protein Daple Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3	O14640 O14641 Q92997 Q9H2H0 Q9P219	CCDC88C CXXC4 DAPLE DVL1 DVL2 DVL3 IDAX KIAA0208 KIAA1509
FOXO-mediated transcription of cell cycle genes	Caveolin-1 Cyclin-G2 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Forkhead box protein G1 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Growth arrest and DNA damage-inducible protein GADD45 alpha Growth/differentiation factor 8 Krueppel-like factor 4 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Poly(rC)-binding protein 4 Protein BTG1 Retinoblastoma-like protein 2	O14793 O43474 O43524 P24522 P38936 P46527 P55316 P57723 P62324 P84022 P98177 Q03135 Q08999 Q12778 Q13485 Q15796 Q16589	AFX AFX1 BTG1 CAP20 CAV CAV1 CCNG2 CDKN1 CDKN1A CDKN1B CIP1 DDIT1 DPC4 EZF FKH2 FKHL1 FKHL2 FKHL3 FKHL4 FKHR FKHRL1 FOXG1 FOXG1A FOXG1B FOXG1C FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 GADD45 GADD45A GDF8 GKLF KIP1 KLF4 MADH2 MADH3 MADH4 MADR2 MDA6 MLLT7 MSTN PCBP4 PIC1 RB2 RBL2 SDI1 SMAD2 SMAD3 SMAD4 WAF1 p27
Defective SLC33A1 causes spastic paraplegia 42 (SPG42)	Acetyl-coenzyme A transporter 1	O00400	ACATN AT1 SLC33A1
APC/C:Cdc20 mediated degradation of mitotic proteins	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic spindle assembly checkpoint protein MAD2A Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 O43684 O60566 P30260 P51668 P51965 P60006 Q12834 Q13042 Q13257 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 BUB1B BUB3 BUBR1 C10orf104 C11orf51 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 MAD2 MAD2L1 MAD3L SFT SSK1 TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S
PKA activation in glucagon signalling	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O95622 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 P63092 Q08462 Q08828 Q5JWF2 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAS GNAS1 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B TSE1
Integrin cell surface interactions	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein Basigin CD44 antigen Cadherin-1 Cartilage oligomeric matrix protein Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain Collagen alpha-1(XIII) chain Collagen alpha-1(XVI) chain Collagen alpha-1(XVIII) chain Collagen alpha-1(XXIII) chain Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain Collagen alpha-3(IV) chain Collagen alpha-3(IX) chain Collagen alpha-4(IV) chain Fibrillin-1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Integrin alpha-10 Integrin alpha-11 Integrin alpha-1 Integrin alpha-2 Integrin alpha-3 Integrin alpha-4 Integrin alpha-5 Integrin alpha-6 Integrin alpha-7 Integrin alpha-8 Integrin alpha-9 Integrin alpha-D Integrin alpha-E Integrin alpha-IIb Integrin alpha-L Integrin alpha-M Integrin alpha-V Integrin alpha-X Integrin beta-1 Integrin beta-2 Integrin beta-3 Integrin beta-5 Integrin beta-6 Integrin beta-7 Integrin beta-8 Integrin-binding sialoprotein Intercellular adhesion molecule 1 Intercellular adhesion molecule 2 Intercellular adhesion molecule 3 Intercellular adhesion molecule 4 Intercellular adhesion molecule 5 Junctional adhesion molecule A Junctional adhesion molecule B Junctional adhesion molecule C Leukocyte surface antigen CD47 Lumican Osteopontin Platelet endothelial cell adhesion molecule Tenascin Thrombospondin-1 Vascular cell adhesion protein 1 Vascular endothelial growth factor receptor 2 Vitronectin	O00468 O75578 P02462 P02671 P02675 P02679 P02751 P04004 P05106 P05107 P05362 P05556 P06756 P07996 P08514 P08572 P08648 P10451 P11215 P12830 P13598 P13612 P16070 P16284 P17301 P18084 P18564 P19320 P20701 P20702 P20849 P21815 P23229 P24821 P26006 P26010 P26012 P32942 P35555 P35613 P35968 P38570 P39060 P49747 P51884 P53420 P53708 P56199 P57087 P98160 Q01955 Q07092 Q08722 Q13349 Q13683 Q13797 Q14050 Q14055 Q14773 Q5TAT6 Q86Y22 Q9BX67 Q9UKX5 Q9UMF0 Q9Y624	AGRIN AGRN BNSP BSG C21orf43 CD11A CD11B CD11C CD18 CD44 CD47 CD49B CD49D CDH1 CDHE COL13A1 COL16A1 COL18A1 COL23A1 COL4A1 COL4A2 COL4A3 COL4A4 COL9A1 COL9A2 COL9A3 COMP CR3A F11R FBN FBN1 FGA FGB FGG FLK1 FN FN1 FNRA FNRB GP2B GP3A HSPG2 HXB IBSP ICAM1 ICAM2 ICAM3 ICAM4 ICAM5 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAB ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB5 ITGB6 ITGB7 ITGB8 JAM1 JAM2 JAM3 JCAM KDR LDC LHR LUM LW MDF2 MDU2 MDU3 MER6 MFI7 MIC4 MSK12 MSK18 MSK8 OPN PECAM1 SLRR2D SPP1 THBS1 TLCN TLN TNC TSP TSP1 UVO VCAM1 VEGFR2 VEJAM VNRA VTN VTNR
Formation of selenosugars for excretion				G61418DU
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 1 Myeloid differentiation primary response protein MyD88 TNF receptor-associated factor 6 Toll-like receptor 7 Toll-like receptor 9	O43187 P51617 Q13233 Q99836 Q9BQ95 Q9NR96 Q9NWZ3 Q9NYK1 Q9Y4K3	ECSIT IRAK IRAK1 IRAK2 IRAK4 MAP3K1 MAPKKK1 MEKK MEKK1 MYD88 RNF85 TLR7 TLR9 TRAF6
GSD 0 (muscle)	Glycogen [starch] synthase, muscle Glycogenin-1	P13807 P46976	GYG GYG1 GYS GYS1
SARS-CoV-2 activates/modulates innate and adaptive immune responses	Aladin Antiviral innate immune response receptor RIG-I Beclin 1-associated autophagy-related key regulator Beclin-1 Beta-2-microglobulin CCHC-type zinc finger nucleic acid binding protein CREB-binding protein E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Envelope small membrane protein HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Importin subunit alpha-1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon alpha/beta receptor 1 Interferon beta Interferon regulatory factor 3 Interferon regulatory factor 7 Interferon-induced helicase C domain-containing protein 1 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase-like 2 Interleukin-17 receptor A Interleukin-17 receptor C Interleukin-17A Interleukin-17F La-related protein 1 Mannan-binding lectin serine protease 1 Mannose-binding protein C Membrane protein Mitochondrial antiviral-signaling protein Mitochondrial import receptor subunit TOM70 Mitogen-activated protein kinase kinase kinase 7 NACHT, LRR and PYD domains-containing protein 12 NACHT, LRR and PYD domains-containing protein 3 NF-kappa-B essential modulator Non-receptor tyrosine-protein kinase TYK2 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Nucleoprotein Nucleotide-binding oligomerization domain-containing protein 1 Nucleotide-binding oligomerization domain-containing protein 2 ORF3a protein ORF6 protein ORF7a protein ORF8 protein ORF9b protein Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphoinositide 3-kinase regulatory subunit 4 Protein SEC13 homolog Protein transport protein Sec23A Protein transport protein Sec24A Protein transport protein Sec24B Protein transport protein Sec24C Protein transport protein Sec24D Pulmonary surfactant-associated protein D Putative HLA class I histocompatibility antigen, alpha chain H Ras GTPase-activating protein-binding protein 1 Ras GTPase-activating protein-binding protein 2 Receptor-interacting serine/threonine-protein kinase 2 Replicase polyprotein 1a Replicase polyprotein 1ab Serine/threonine-protein kinase TBK1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 2 Small COPII coat GTPase SAR1B Spike glycoprotein Stimulator of interferon genes protein Suppressor of IKBKE 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 3 TNF receptor-associated factor 6 Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 7 Toll-like receptor 8 Triokinase/FMN cyclase Tyrosine-protein kinase JAK1 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-like protein ISG15 mRNA export factor RAE1	A8CG34 O14920 O15111 O15504 O43187 O43318 O43353 O60603 O75694 O94826 O94855 O95486 O95487 O95786 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P01889 P01893 P04439 P05013 P05014 P05015 P05161 P07900 P08238 P0DTC1 P0DTC2 P0DTC3 P0DTC4 P0DTC5 P0DTC6 P0DTC7 P0DTC8 P0DTC9 P0DTD1 P0DTD2 P10321 P11226 P12270 P13747 P17181 P17693 P23458 P29350 P29597 P30511 P32881 P35247 P35658 P37198 P42224 P48740 P49790 P49792 P51617 P52292 P52630 P53992 P55735 P57740 P59046 P61088 P61769 P62633 P78406 Q06124 Q12769 Q13114 Q13283 Q13404 Q14164 Q14258 Q14457 Q14653 Q15399 Q15436 Q15750 Q16552 Q3LXA3 Q5SRE5 Q6PKG0 Q6ZNE5 Q7Z3B4 Q7Z434 Q86WV6 Q8IUD6 Q8N1F7 Q8N5C8 Q8NAC3 Q8NEB9 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q92793 Q92985 Q96F46 Q96HA1 Q96P20 Q96PD4 Q99567 Q99570 Q9BRV8 Q9BTX1 Q9BW27 Q9BYX4 Q9C037 Q9HC29 Q9NR97 Q9NRG9 Q9NYJ8 Q9NYK1 Q9UHD2 Q9UKX7 Q9UN86 Q9Y239 Q9Y4K3 Q9Y6B6 Q9Y6K9	3a 6 7a 8 9b AAAS ADRACALA ATG14 ATG14L B2M BECN1 BLU C1orf7 C7orf14 CAIN CAN CAP-1 CARD15 CARD4 CARDIAK CBP CG1 CHUK CIAS1 CNBP COLEC1 COLEC7 CRAF1 CRARF CRARF1 CREBBP CROC1 CTLA8 D3S1231E DAK DDX58 E EFP ERIS FIP3 G1P2 G3BP G3BP1 G3BP2 GT197 HCP HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB IFB IFIH1 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR IFNAR1 IFNB IFNB1 IKBKB IKBKE IKBKG IKKA IKKB IKKE IKKI IL17 IL17A IL17F IL17R IL17RA IL17RC IPS1 IRAK IRAK1 IRAK2 IRF3 IRF7 ISG15 JAK1 JAK1A JAK1B KIAA0012 KIAA0023 KIAA0079 KIAA0095 KIAA0151 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0660 KIAA0719 KIAA0731 KIAA0733 KIAA0755 KIAA0791 KIAA0831 KIAA0906 KIAA1271 KPNA2 LARP LARP1 M MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MASP1 MAVS MBL MBL2 MDA5 MITA MP44 MRNP41 N NAK NALP12 NALP3 NDC1 NEMO NLRP12 NLRP3 NOD1 NOD2 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 PIK3C3 PIK3R4 POM121 POM121A POM121C PRSS5 PSPD PTP1C PTP2C PTPN11 PTPN6 PYPAF1 PYPAF7 RAE1 RANBP2 RCH1 RH116 RICK RIGI RIP2 RIPK2 RNF135 RNF147 RNF163 RNF85 RNF87 RNO S SAR1B SARA2 SARB SEC13 SEC13A SEC13L1 SEC13R SEC23A SEC24A SEC24B SEC24C SEC24D SFTP4 SFTPD SHPTP2 SIKE SIKE1 SRP1 STAT1 STAT2 STING STING1 TAB1 TAB2 TAB3 TAK1 TBK1 TCF16 TIL4 TKFC TLR1 TLR2 TLR7 TLR8 TMEM173 TMEM48 TOM70 TOMM70 TOMM70A TPR TRAF3 TRAF6 TRAFAMN TRIM25 TRIM4 TYK2 UBE2N UBE2V UBE2V1 UCRP UEV1 VISA VPS15 VPS34 ZNF147 ZNF9 rep
Defective ALG6 causes CDG-1c	Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase	Q9Y672	ALG6
Toxicity of botulinum toxin type B (botB)	Botulinum neurotoxin type B HA-17 HA-33 protein Ha70 protein NTNHA Synaptotagmin-1 Synaptotagmin-2 Vesicle-associated membrane protein 2	P10844 P21579 P63027 Q45877 Q45878 Q57230 Q8N9I0 Q9LBS8	HA HA-17 HA-33 SVP65 SYB2 SYT SYT1 SYT2 VAMP2 botB ha17 ha34 ha70 ntnha
Ras activation upon Ca2+ influx through NMDA receptor	Alpha-actinin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Disks large homolog 1 Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 GTPase HRas GTPase NRas Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2D Leucine-rich repeat-containing protein 7 Neurofilament light polypeptide Ras-specific guanine nucleotide-releasing factor 1 Ras-specific guanine nucleotide-releasing factor 2	O14827 O15399 P01111 P01112 P07196 P0DP23 P35609 P78352 Q05586 Q12959 Q13224 Q13554 Q13555 Q13557 Q13972 Q15700 Q92796 Q96NW7 Q9UQM7	ACTN2 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CDC25 DLG1 DLG2 DLG3 DLG4 GNRP GRF1 GRF2 GRIN1 GRIN2B GRIN2D GluN2D HRAS HRAS1 KIAA0968 KIAA1232 KIAA1365 LAP1 LRRC7 NEFL NF68 NFL NMDAR1 NMDAR2B NMDAR2D NRAS PSD95 RASGRF1 RASGRF2
Clathrin-mediated endocytosis	ADP-ribosylation factor 6 ADP-ribosylation factor GTPase-activating protein 1 AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma AP2-associated protein kinase 1 Actin nucleation-promoting factor WASL Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Adaptin ear-binding coat-associated protein 1 Adaptin ear-binding coat-associated protein 2 Amphiphysin Amphiregulin Apolipoprotein B-100 Arf-GAP domain and FG repeat-containing protein 1 Auxilin Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 Cation-dependent mannose-6-phosphate receptor Cation-independent mannose-6-phosphate receptor Cdc42-interacting protein 4 Clathrin coat assembly protein AP180 Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Cyclin-G-associated kinase Cystic fibrosis transmembrane conductance regulator Disabled homolog 2 Dynamin-1 Dynamin-2 Dynamin-3 Dyslexia-associated protein KIAA0319 E3 ubiquitin-protein ligase CBL Endophilin-A1 Endophilin-A2 Endophilin-A3 Epidermal growth factor receptor substrate 15-like 1 Epidermal growth factor receptor substrate 15 Epidermal growth factor receptor Epigen Epsin-1 Epsin-2 F-BAR domain only protein 1 F-BAR domain only protein 2 Formin-binding protein 1-like Formin-binding protein 1 Frizzled-4 GTPase-activating protein and VPS9 domain-containing protein 1 Heat shock cognate 71 kDa protein Hepatocyte growth factor-regulated tyrosine kinase substrate Huntingtin-interacting protein 1-related protein Huntingtin-interacting protein 1 Inositol polyphosphate 5-phosphatase OCRL Interleukin-7 receptor subunit alpha Intersectin-1 Intersectin-2 Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 Low-density lipoprotein receptor Lysosome membrane protein 2 Muscarinic acetylcholine receptor M2 Myc box-dependent-interacting protein 1 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Phosphatidylinositol-binding clathrin assembly protein Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein Wnt-5a Protein kinase C and casein kinase substrate in neurons protein 1 Protein kinase C and casein kinase substrate in neurons protein 2 Protein kinase C and casein kinase substrate in neurons protein 3 Protransforming growth factor alpha RalBP1-associated Eps domain-containing protein 1 RalBP1-associated Eps domain-containing protein 2 Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C SH3 domain-containing kinase-binding protein 1 SH3-containing GRB2-like protein 3-interacting protein 1 Segment polarity protein dishevelled homolog DVL-2 Serotransferrin Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Solute carrier family 2, facilitated glucose transporter member 8 Sorting nexin-18 Sorting nexin-9 Src substrate cortactin Stonin-1 Stonin-2 Substance-P receptor Synaptojanin-1 Synaptojanin-2 Synaptotagmin-11 Synaptotagmin-1 Synaptotagmin-2 Synaptotagmin-8 Synaptotagmin-9 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Trans-Golgi network integral membrane protein 2 Transferrin receptor protein 1 Type-1 angiotensin II receptor Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 4 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8 Vesicular acetylcholine transporter	O00291 O00401 O00443 O00499 O14526 O14641 O14944 O14964 O14976 O15056 O15144 O15145 O15511 O43426 O43493 O60331 O60641 O75061 O75146 O75379 O75886 O94973 O95208 O95782 P00533 P01130 P01133 P01135 P01185 P01730 P02786 P02787 P04114 P04234 P07550 P08172 P09496 P09497 P09693 P0CG47 P0CG48 P11142 P11717 P13569 P15514 P16871 P20339 P20645 P21579 P22681 P25103 P30518 P30556 P32121 P35070 P41221 P42566 P49407 P49418 P50570 P51148 P51809 P52594 P53675 P53680 P59998 P61020 P61158 P61160 P62330 P62979 P62987 P63010 P63027 P98082 P98164 Q00610 Q01968 Q05193 Q0JRZ9 Q13492 Q14108 Q14247 Q14C86 Q15642 Q15811 Q15836 Q16572 Q2M2I8 Q5SW96 Q5T0N5 Q5VV43 Q6UW88 Q86SS6 Q8N6T3 Q8N9I0 Q8NBV8 Q8NC96 Q8NFH8 Q8WXE9 Q92747 Q92783 Q96B97 Q96CW1 Q96D71 Q96RF0 Q96RU3 Q99075 Q99961 Q99962 Q99963 Q9BQI5 Q9BT88 Q9BV40 Q9BY11 Q9NVZ3 Q9NY64 Q9NZM3 Q9UBC2 Q9UKS6 Q9ULV1 Q9UNF0 Q9UQ16 Q9Y5X1 Q9Y6I3 Q9Y6Q2	AAK1 ABCC7 ACTR2 ACTR3 ADHR ADRB2 ADRB2R ADTAA ADTAB ADTB2 AF1P AGFG1 AGTR1 AGTR1A AGTR1B AMPH AMPH1 AMPHL AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB ARB2 ARC16 ARC20 ARC21 ARC34 AREG AREGB ARF1GAP ARF6 ARFGAP1 ARH ARP2 ARP3 ARPC1A ARPC2 ARPC3 ARPC4 ARPC5 ARR1 ARR2 ARRB1 ARRB2 ARVP AT2R1 AT2R1B AVP AVPR2 B2AR BIN1 BTC C1orf39 CALM CBL CBL2 CD36L2 CD3D CD3G CD4 CFTR CHRM2 CIN85 CIP4 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD CNSA1 CNSA2 CNSA3 CTTN DAB2 DIR DIR3 DNAJC26 DNAJC6 DNM DNM1 DNM2 DNM3 DOC2 DTR DTS DVL2 DYN2 EGF EGFR EMS1 EPGN EPN1 EPN2 EPS15 EPS15L1 EPS15R ERBB ERBB1 EREG FBP17 FCHO1 FCHO2 FNBP1 FNBP1L FZD4 GAK GAPEX5 GAPVD1 GLUT8 GLUTX1 HBEGF HBP HEGFL HER1 HGS HIP1 HIP12 HIP1R HIP9 HRB HRS HSC70 HSP73 HSPA10 HSPA8 HYPJ IGF2R IL7R ITSN ITSN1 ITSN2 KIAA0034 KIAA0080 KIAA0109 KIAA0290 KIAA0319 KIAA0348 KIAA0473 KIAA0554 KIAA0589 KIAA0655 KIAA0656 KIAA0820 KIAA0899 KIAA0910 KIAA1048 KIAA1065 KIAA1256 KIAA1379 KIAA1521 LDLR LDLRAP1 LIMP2 LIMPII LRP2 M6PR MPR46 MPRD MPRI NECAP1 NECAP2 NK1R OCRL OCRL1 PACSIN1 PACSIN2 PACSIN3 PICALM PIK3C2A PIP5K1C POB1 RAB RAB5 RAB5A RAB5B RAB5C RABL RAP6 REPS1 REPS2 RIP RNF55 RPS27A SALF SBLF SCARB2 SDGF SGIP1 SH3D1A SH3D1B SH3D2A SH3D2B SH3D2C SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SH3PX1 SH3PXD3A SH3PXD3B SLC18A3 SLC2A8 SNAP91 SNX18 SNX9 SOP2L STAM STAM1 STAM2 STN1 STN2 STNB STON1 STON2 STOT STP SVP65 SWAP SYB2 SYB3 SYBL1 SYNJ1 SYNJ2 SYT SYT1 SYT11 SYT2 SYT8 SYT9 T3D T3G TAC1R TACR1 TF TFRC TGFA TGN46 TGN51 TGOLN2 TOCA1 TRIP10 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 V2R VACHT VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 VP WASL WNT5A
Removal of the Flap Intermediate	DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA primase large subunit DNA primase small subunit DNA replication ATP-dependent helicase/nuclease DNA2 Flap endonuclease 1 Proliferating cell nuclear antigen Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit	P09884 P12004 P15927 P27694 P28340 P35244 P39748 P49005 P49642 P49643 P51530 Q14181 Q15054 Q9HCU8	DNA2 DNA2L FEN1 KIAA0039 KIAA0083 PCNA POLA POLA1 POLA2 POLD POLD1 POLD2 POLD3 POLD4 POLDS PRIM1 PRIM2 PRIM2A RAD2 REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70
Inhibition of replication initiation of damaged DNA by RB1/E2F1	DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA primase large subunit DNA primase small subunit Retinoblastoma-associated protein Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1	P06400 P09884 P30153 P30154 P49642 P49643 P62714 P67775 Q01094 Q14181 Q14186 Q14188 Q9Y5P8	DP1 DP2 E2F1 POLA POLA1 POLA2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R3B PPP2R3L PRIM1 PRIM2 PRIM2A RB1 RBBP3 TFDP1 TFDP2
Defective visual phototransduction due to OPN1LW loss of function	Long-wave-sensitive opsin 1	P04000	OPN1LW RCP
Defective HEXA causes GM2G1	Beta-hexosaminidase subunit alpha	P06865	HEXA	G20239CJ
Peroxisomal protein import	2-Hydroxyacid oxidase 1 2-Hydroxyacid oxidase 2 2-hydroxyacyl-CoA lyase 1 3-ketoacyl-CoA thiolase, peroxisomal AN1-type zinc finger protein 6 Acyl-coenzyme A diphosphatase NUDT19 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 8 Alanine--glyoxylate aminotransferase Alkyldihydroxyacetonephosphate synthase, peroxisomal Alpha-methylacyl-CoA racemase Bifunctional epoxide hydrolase 2 Bile acid-CoA Carnitine O-acetyltransferase Catalase D-amino-acid oxidase D-aspartate oxidase Dehydrogenase/reductase SDR family member 4 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Dihydroxyacetone phosphate acyltransferase Glutathione S-transferase kappa 1 Hydroxymethylglutaryl-CoA lyase, mitochondrial Insulin-degrading enzyme Isocitrate dehydrogenase [NADP] cytoplasmic Lon protease homolog 2, peroxisomal Long-chain fatty acid transport protein 2 Nitric oxide synthase, inducible Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal ATPase PEX1 Peroxisomal ATPase PEX6 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal acyl-coenzyme A oxidase 3 Peroxisomal bifunctional enzyme Peroxisomal carnitine O-octanoyltransferase Peroxisomal coenzyme A diphosphatase NUDT7 Peroxisomal leader peptide-processing protease Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal multifunctional enzyme type 2 Peroxisomal sarcosine oxidase Peroxisomal succinyl-coenzyme A thioesterase Peroxisomal targeting signal 2 receptor Peroxisomal trans-2-enoyl-CoA reductase Peroxisome assembly protein 12 Peroxisome assembly protein 26 Peroxisome biogenesis factor 10 Peroxisome biogenesis factor 2 Phytanoyl-CoA dioxygenase, peroxisomal Polyubiquitin-B Polyubiquitin-C Protein Mpv17 Sterol carrier protein 2 Ubiquitin carboxyl-terminal hydrolase 9X Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MXV4 O00116 O00623 O00628 O14734 O14832 O14975 O15228 O15254 O43933 O60683 O75381 O75874 P04040 P09110 P0C024 P0CG47 P0CG48 P14735 P14920 P21549 P22307 P28328 P34913 P35228 P35914 P39210 P43155 P49753 P51659 P51668 P61077 P62837 P62979 P62987 Q08426 Q13011 Q13608 Q14032 Q15067 Q2T9J0 Q6FIF0 Q6QHF9 Q7Z412 Q86WA8 Q8N9L9 Q92968 Q93008 Q99424 Q99489 Q9BTZ2 Q9BY49 Q9NUI1 Q9NYQ3 Q9P0Z9 Q9UHK6 Q9UJ83 Q9UJM8 Q9UKG9 Q9Y2Q3	ACAA ACAA1 ACOT2 ACOT4 ACOT8 ACOX ACOX1 ACOX2 ACOX3 ACSVL1 ACTEIII AGPS AGT1 AGXT AMACR AWP1 BAAT BRCOX CAT CAT1 COT CRAT CROT DAMOX DAO DAPAT DDO DECR2 DFFRX DHAPAT DHRS4 ECH1 ECHD EDH17B4 EHHADH EPHX2 FACVL1 FAM FATP2 GNPAT GOX1 GSTK1 HACL1 HAO1 HAO2 HAOX2 HMGCL HPCL HPCL2 HSD17B4 IDE IDH1 LONP LONP2 LPIPOX MPV17 NOS2 NOS2A NUDT19 NUDT7 PAF1 PAF3 PAHX PAO PAOX PDCR PECR PEX1 PEX10 PEX12 PEX13 PEX14 PEX2 PEX26 PEX6 PEX7 PHYH PHYH2 PICD PIPOX PMP3 PMP35 PRCOX PSO PTE1 PTE2 PTE2A PTE2B PTEIB PTHIO PTS2R PUBC1 PXAAA1 PXMP3 RNF69 RNF72 RPS27A SCP2 SDR17C1 SDR25C2 SDR29C1 SDR8C1 SFT SLC27A2 SPAT TYSND1 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 USP9 USP9X VLACS ZA20D3 ZFAND6

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